“…The severity of eruptions on lesions is evaluated on a 4-point scale (0: none, 1: mild, 2: moderate, 3: severe) by scoring the erythema, oedema, oozing, excoriation, lichenification, and xerosis. SCORAD is calculated by the equation A/5 + 7 × B/2 + C. In this equation, A is the percentage of body area with a skin rash, B is the total score of erythema, oedema, oozing, excoriation, lichenification, and xerosis, each of which was evaluated on a 4-point scale, and C is the visual analogue scale (VAS, a scale from 0 to 10) for subjective assessment of both itching and sleep loss[ 18 - 20 ]. It will be measured at treatment initiation, at two weeks after the first medication administration, at four weeks after the first medication administration, and at eight weeks after the first medication administration.…”