“…Both Chinese herbs and the gut microbiota had the regulation of innate immunity (Wójcik et al, 2009;Wang et al, 2019). Therefore, Chinese herbs rarely has a direct antibacterial ability, but it can rely on inhibiting bacterial growth proteins to inhibit infection (Si et al, 2016) or enhance the regulatory factors that promote innate immunity to achieve antibacterial effect (Ma et al, 2013(Ma et al, , 2018Si et al, 2016;Wang et al, 2016;Yang et al, 2018;Pascale et al, 2019). Consisting with the long-term research of our labs that the integrity of barrier cells such as epithelial cells and endothelial cells contributed to the bactericidal function of immune cells such as neutrophils (Liu et al, 2016).…”