Chinese Food Cooking and Lung Cancer in Women Nonsmokers

Ko, Ying‐Chin; Li, Cheng; Lee, Chien-Hung; Huang, Jhi-Jhu; Huang, Ming‐Shyan; Kao, Eing-Long; Wang, Hwei-Zu; Lin, Hsiang‐Ju

doi:10.1093/oxfordjournals.aje.a010181

Cited by 243 publications

(166 citation statements)

References 32 publications

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“…Our results showed that nonsmoking female lung adenocarcinoma was closely related to cooking oil fumes exposure. There are studies in Shanghai, Taiwan, Hong Kong and other places reporting the significant association of lung cancer in women with expose to cooking oil fume (Zhong et al, 1999;Ko et al, 2000;Yu et al, 2006;Pan et al, 2008). Previous studies have shown that sugar, proteins, fat and amino acids can release some harmful substances, such as particulate matter (PM), polycyclic aromatic hydrocarbons, aromatic amines, nitro-PAHs, and aldehydes under the hightemperature treatment (Vainiotalo et al, 1993;Li et al, 1994;Wu et al, 1998;Chiang et al, 1999;Lund et al, 2006).…”

Section: Discussionmentioning

confidence: 99%

TP63 Gene Polymorphisms, Cooking Oil Fume Exposure and Risk of Lung Adenocarcinoma in Chinese Non-smoking Females

Yin

Cui²,

Ren³

et al. 2013

Asian Pacific Journal of Cancer Prevention

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-1.01, P=0.059). Our results showed that exposure to cooking oil fumes was associated with increased risk of lung adenocarcinoma in Chinese nonsmoking females (adjusted OR=1.58, 95%CI=1.11-2.25, P=0.011). However, we did not observe a significant interaction of cooking oil fumes and TP63 polymorphisms. Conclusion: TP63 polymorphism might be a genetic susceptibility factor for lung adenocarcinoma in Chinese non-smoking females, but no significant interaction was found with cooking oil fume exposure.

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Section: Discussionmentioning

confidence: 99%

TP63 Gene Polymorphisms, Cooking Oil Fume Exposure and Risk of Lung Adenocarcinoma in Chinese Non-smoking Females

Yin

Cui²,

Ren³

et al. 2013

Asian Pacific Journal of Cancer Prevention

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“…29,30 Few women in China are smokers; the 2002 survey suggested that only about 1.5-3% are current daily smok- ers, 29 so that the moderately raised rates, which are continuing to increase, must have another explanation. The most popular explanation offered is exposure to environmental smoke, particularly cooking fumes 31,32 and indoor smoky coal emissions. 33 One might expect such exposures to diminish in future, with continuing improvements in living conditions in urban areas.…”

Section: Discussionmentioning

confidence: 99%

Trends in the incidence of cancer in Qidong, China, 1978–2002

Chen

Zhu

Parkin

et al. 2006

Intl Journal of Cancer

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A population-based cancer registry was established in Qidong, Jiangsu Province, China, in 1972, and the trends in incidence rates of the major cancer sites have been analyzed for a 25-year period, 1978-2002. Five-year age-specific rates, crude incidence rates, world age-standardized rates (ASR), percent change (PC) and annual percent change (APC) were calculated using annual data on population size, and estimates of its age structure. The indices of histological verification of diagnosis, death certificate only and proportion of mortality to incidence were employed for assessing the registration quality. A total of 51,933 incident cases of cancer were registered in Qidong from years 1978 to 2002, with a maleto-female sex ratio of 1.9:1. Crude incidence increased markedly over the 25-year period (PC and APC of 155.6% and 12.1%, respectively), but ASR showed a slight decrease (20.4% in males, and 20.3% in females), indicating that the major part of this is due to population ageing. The leading cancer sites in rank were liver (average ASR 5 50.8 per 100,000), stomach (26.7), lung (22.7), colon-rectum (8.9), oesophagus (7.4) and breast (5.4). Cancers of liver, lung, colon-rectum and female breast all showed increases in incidence during the study period, with APCs (ASR) of 10.1%, 11.7% and 11.4% for males, and 10.2%, 10.9%, 11.9% and 11.1% for females, while the cancers of stomach (APC: 23.2% in male, and 22.4% in female) and cervix (APC: 24.7%) showed notable declines. Examination of age-specific rates showed declining trends in the younger generations for liver cancer, but increases for cervix cancer. The results underline the increasing importance of cancer as a cause of mortality and morbidity in a population that is ageing and undergoing profound changes in socioeconomic development and lifestyle. The cancers of high lethality that have been common in the Chinese population (liver, stomach, oesophagus) are showing some evidence of decline, at least in younger generations, but they remain major problems. At the same time, the cancers associated with economically ''developed'' societies-lung, colon-rectum and female breastare showing increases. The population-based cancer registry is an indispensable tool for providing data for planning and evaluation of programmes for cancer control in all societies. ' 2006 Wiley-Liss, Inc.

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“…[7][8][9] The protective effect of dietary fruit and vegetable in the development of lung cancer has been of considerable interest since it was first described in the 1970s. 10 Recent studies support an effect of total fruit and vegetable intake rather than of individual micronutrients, 11 with the evidence being most consistent for Brassica vegetables, which are rich in isothiocyanates, potent inhibitors of NNK carcinogenesis.…”

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confidence: 99%

Diet, reproductive factors and lung cancer risk among Chinese women in Singapore: Evidence for a protective effect of soy in nonsmokers

Seow

Poh

Teh

et al. 2001

Intl Journal of Cancer

106

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The factors associated with risk of lung cancer among nonsmokers have not been fully elucidated, but dietary factors have consistently been shown to play a role. Chinese women are unique in having a high incidence of lung cancer despite a low smoking prevalence. This population is also known to have a high intake of soy, a dietary source of phytoestrogens. We conducted a hospital-based case-control study among Singapore Chinese women, comprising 303 cases and 765 age-matched controls, of whom 176 cases and 663 controls were lifetime nonsmokers. Data on demographic background, reproductive factors and dietary intake of fruit, vegetables and soy foods were obtained by in-person interview. We observed an inverse association between intake of total, cruciferous and non-cruciferous vegetables and risk of lung cancer among smokers. Although smokers in the highest tertile of fruit intake also had a lower risk, this was not statistically significant. Higher intake of soy foods significantly reduced risk of lung cancer among lifetime nonsmokers, but not among smokers. When soy isoflavonoid intake in mg/week was computed based on frequency and portion size of intake of eight common local soy foods, the adjusted OR among nonsmokers for the highest tertile compared to the lowest was 0.56, 95% CI 0.37-0.85 (p for trend <0.01). Fruit intake was also significantly associated with reduced lung cancer risk among nonsmokers, but the effect was not significant after adjustment for soy intake. On the other hand, soy intake remained an independent predictor of risk after controlling for fruit intake. Reproductive effects were also primarily confined to lifetime nonsmokers, among whom having 3 or more livebirths (adjusted OR 0.65, 0.44 -0.96) and a menstrual cycle length of more than 30 days (OR 0.46, 0.25-0.84) accorded a significantly reduced risk of lung cancer. Place of birth was significantly associated with risk among nonsmokers (OR 2.6, 1.7-3.9 for China-born vs. local born) but not among smokers. When analysis was restricted to nonsmokers with adenocarcinomas, the dietary effects were consistent or enhanced. On stepwise regression, soy intake and cycle length emerged as the independent dietary and reproductive predictors of lung cancer risk in nonsmokers. These findings are consistent with other evidence suggesting an involvement of estrogen-related pathways in lung cancer among non-smoking women.

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Chinese Food Cooking and Lung Cancer in Women Nonsmokers

Cited by 243 publications

References 32 publications

TP63 Gene Polymorphisms, Cooking Oil Fume Exposure and Risk of Lung Adenocarcinoma in Chinese Non-smoking Females

TP63 Gene Polymorphisms, Cooking Oil Fume Exposure and Risk of Lung Adenocarcinoma in Chinese Non-smoking Females

Trends in the incidence of cancer in Qidong, China, 1978–2002

Diet, reproductive factors and lung cancer risk among Chinese women in Singapore: Evidence for a protective effect of soy in nonsmokers

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