China's First Tera-Hertz Free Electron Laser Oscillator

Li, Ming; Yang, Xinfan; Xu, Zuyan; Dai, Wei; Wang, Hanbin; Xiao, Dexin; Shu, Xiaojian; Lu, Xiangyang; Huang, Wenhui; Dou, Yuhuan

doi:10.1109/icmmt.2018.8563679

Cited by 3 publications

(3 citation statements)

References 7 publications

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“…The CTFEL was used to expose RAW264.7 cells to different frequencies of THz radiation [ 36 ]. All of the experiments were conducted at a frequency of 2.42 THz or 3.1 THz, with a pulse width of 2 ms, a peak power per pulse of 1.6 W, and a repetition rate of 10 Hz.…”

Section: Methodsmentioning

confidence: 99%

Spectral Characteristics and Functional Responses of Phospholipid Bilayers in the Terahertz Band

Lin

Wang

et al. 2023

IJMS

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Understanding the vibrational information encoded within the terahertz (THz) spectrum of biomolecules is critical for guiding the exploration of its functional responses to specific THz radiation wavelengths. This study investigated several important phospholipid components of biological membranes—distearoyl phosphatidylethanolamine (DSPE), dipalmitoyl phosphatidylcholine (DPPC), sphingosine phosphorylcholine (SPH), and lecithin bilayer—using THz time-domain spectroscopy. We observed similar spectral patterns for DPPC, SPH, and the lecithin bilayer, all of which contain the choline group as the hydrophilic head. Notably, the spectrum of DSPE, which has an ethanolamine head group, was different. Interestingly, density functional theory calculations confirmed that the absorption peak common to DSPE and DPPC at approximately 3.0 THz originated from a collective vibration of their similar hydrophobic tails. Accordingly, the cell membrane fluidity of RAW264.7 macrophages with irradiation at 3.1 THz was significantly enhanced, leading to improved phagocytosis. Our results highlight the importance of the spectral characteristics of the phospholipid bilayers when studying their functional responses in the THz band and suggest that irradiation at 3.1 THz is a potential non-invasive strategy to increase the fluidity of phospholipid bilayers for biomedical applications such as immune activation or drug administration.

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Section: Methodsmentioning

confidence: 99%

Spectral Characteristics and Functional Responses of Phospholipid Bilayers in the Terahertz Band

Lin

Wang

et al. 2023

IJMS

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“…Copyright Springer, 2018. The unique properties of FEL oscillators, in particular to fill the spectral gap for coherent light sources in the visible to microwave spectral range, resulted quickly in the establishment of several facilities for applied research. The characteristics of user facilities using FEL oscillators depends, in part, on the accelerator technology used, which includes electrostatic acceleration [6][7][8][9], energy recovery linear accelerators (linacs) [10][11][12][13][14][15], nonrecovery linacs [16][17][18][19][20][21][22][23][24][25][26][27][28][29][30], microtrons [31,32] and synchrotrons [33][34][35][36][37]. Research performed at these user facilities includes, amongst others, biological and material science [38].…”

Section: Introductionmentioning

confidence: 99%

Three-Dimensional, Time-Dependent Analysis of High- and Low-Q Free-Electron Laser Oscillators

Slot

Freund

2021

Applied Sciences

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Free-electron lasers (FELs) have been designed to operate over virtually the entire electromagnetic spectrum, from microwaves through to X-rays, and in a variety of configurations, including amplifiers and oscillators. Oscillators can operate in both the low and high gain regime and are typically used to improve the spatial and temporal coherence of the light generated. We will discuss various FEL oscillators, ranging from systems with high-quality resonators combined with low-gain undulators, to systems with a low-quality resonator combined with a high-gain undulator line. The FEL gain code MINERVA and wavefront propagation code OPC are used to model the FEL interaction within the undulator and the propagation in the remainder of the oscillator, respectively. We will not only include experimental data for the various systems for comparison when available, but also present, for selected cases, how the two codes can be used to study the effect of mirror aberrations and thermal mirror deformation on FEL performance.

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“…facilities for applied research. The characteristics of user facilities using FEL oscillators depends in part on the accelerator technology used, which include electrostatic acceleration [5][6][7][8], energy recovery linear accelerators (linacs) [9][10][11][12][13][14], non-recovery linacs [15][16][17][18][19][20][21][22][23][24][25][26][27][28][29], microtrons [30,31] and synchrotrons [32][33][34][35][36]. Research performed at these user facilities includes amongst others biological and material science [37].…”

Section: Introductionmentioning

confidence: 99%

Three-dimensional, time-dependent analysis of high- and low-Q free-electron laser oscillators

Slot¹,

Freund²

2021

Preprint

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Free-electron lasers (FELs) have been designed to operate over virtually the entire electromagnetic spectrum from microwaves through x-rays and in a variety of configurations including amplifiers and oscillators. Oscillators can operate in both the low and high gain regime and are typically used to improve the spatial and temporal coherence of the light generated. We will discuss various FEL oscillators ranging from systems with high-quality resonators combined with low-gain undulators to systems with a low-quality resonator combined with a high-gain undulator line. The FEL gain code MINERVA and wavefront propagation code OPC are used to model the FEL interaction within the undulator and the propagation in the remainder of the oscillator, respectively. We will not only include experimental data for the various systems for comparison when available, but also present for selected cases how the two codes can be used to study the effect of mirror aberrations and thermal mirror deformation on FEL performance.

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China's First Tera-Hertz Free Electron Laser Oscillator

Cited by 3 publications

References 7 publications

Spectral Characteristics and Functional Responses of Phospholipid Bilayers in the Terahertz Band

Spectral Characteristics and Functional Responses of Phospholipid Bilayers in the Terahertz Band

Three-Dimensional, Time-Dependent Analysis of High- and Low-Q Free-Electron Laser Oscillators

Three-dimensional, time-dependent analysis of high- and low-Q free-electron laser oscillators

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