“…[4][5][6][7] However, when defects are extensive, complex and three-dimensional in nature, the conventional fibular composite flap whose various components, being interdependent on each other for vascularization and survival, are unable to be separated, is not maneuverable enough to inset to cover the defects as described above. 8 Meanwhile, when the ends of a bone defect are not well vascularized, modification should be made to the conventional composite fibular flap to include excessive vascularized periosteum which can be wrapped around the graft-and host contact so that bone union can be enhanced by the osteogenic and angiogenic property of the periosteum. Consequently, in this paper, we presented an in-depth anatomical study into the peroneal vascular system, providing the anatomical basis for harvest various peroneal artery-based chimeric composite flaps for repair of compound tissue defects with complex geometric distribution.…”