Children with congenital hearing loss – a vulnerable group

Holseth, Kristin; Mattson, Tone Stokkereit

doi:10.4045/tidsskr.18.0939

Cited by 4 publications

(2 citation statements)

References 17 publications

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“…There are serious negative consequences associated with undetected HL such as speech, language and cognitive delays, poor social adjustment, and academic achievement [ 11 – 13 ]. Physical and psychological morbidities may also co-exist with HL [ 14 ] and more than a quarter of children with HL have additional disabling conditions [ 15 , 16 ]. An aetiologic factor can be identified in 50–60% of HL cases–a genetic cause is present in 60% of infants with HL, peripartum problems in 21%, and cytomegalovirus (CMV) infection in 19% [ 17 – 21 ].…”

Section: Introductionmentioning

confidence: 99%

UK and US risk factors for hearing loss in neonatal intensive care unit infants

Thornton,

Hoare,

Yates

et al. 2024

PLoS ONE

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Importance Early detection and intervention of hearing loss may mitigate negative effects on children’s development. Children who were admitted to the neonatal intensive care unit (NICU) as babies are particularly susceptible to hearing loss and risk factors are vital for surveillance. Design, setting and participants This single-centre retrospective cohort study included data from 142 inborn infants who had been admitted to the NICU in a tertiary regional referral centre. Data were recorded for 71 infants with confirmed permanent congenital hearing loss hearing loss. To determine impact of NICU admission independently of prematurity, babies were individually matched with 71 inborn infants on gestational age, birthweight, and sex. Main outcomes and measures Neonatal indicators were recorded for all children with permanent congenital hearing loss. Presence of UK and US risk factors for hearing loss were collected on the neonatal population with hearing loss and for the matched controls. Results A fifth (21%) of babies with hearing loss had one or more UK risk factors whereas most (86%) had at least one US risk factor. False positives would be evident if US factors were used whereas the matched controls had no UK risk factors. Ten babies who at birth had no UK or US risk factors did not have any significant neonatal indicators identified in their records, one was ventilated for one day and two had a genetic anomaly. Conclusions and relevance Current risk factors for hearing loss we identified for follow-up in this high-risk group are highly specific for congenital hearing loss. UK risk factors were highly specific for hearing loss but not sensitive and conversely, US risk factors are sensitive but not specific so false positives would be recorded. A national study of neonatal indicators could provide the utility to test which combinations of risk factors provide high sensitivity without losing specificity.

show abstract

Section: Introductionmentioning

confidence: 99%

UK and US risk factors for hearing loss in neonatal intensive care unit infants

Thornton,

Hoare,

Yates

et al. 2024

PLoS ONE

View full text Add to dashboard Cite

show abstract

“…There are serious negative consequences associated with undetected HL such as speech, language and cognitive delays, poor social adjustment, and academic achievement [11][12][13]. Physical and psychological morbidities may also co-exist with HL [14] and more than a quarter of children with HL have additional disabling conditions [15,16]. An aetiologic factor can be identified in 50-60% of HL cases -a genetic cause is present in 60% of infants with HL, peripartum problems in 21%, and cytomegalovirus (CMV) infection in 19% [17][18][19][20][21].…”

Section: Introductionmentioning

confidence: 99%

UK and US risk factors for hearing loss in neonatal intensive care unit infants

Thornton,

Hoare,

Yates

et al. 2023

Preprint

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ImportanceEarly detection and intervention of hearing loss may mitigate negative effects on children’s development. Children who were admitted to the neonatal intensive care unit (NICU) as babies are particularly susceptible to hearing loss and risk factors are vital for surveillance.Design, Setting and ParticipantsThis single-centre retrospective cohort study included data from 142 inborn infants who had been admitted to the NICU in a tertiary regional referral centre. Data were recorded for 71 infants with confirmed permanent congenital hearing loss hearing loss. To determine impact of NICU admission independently of prematurity babies were individually matched with 71 inborn infants on gestational age, birthweight, and sex.Main Outcomes and MeasuresNeonatal indicators were recorded for all children with permanent congenital hearing loss. Presence of UK and US risk factors for hearing loss were collected on the neonatal population with hearing loss and for the matched controls.ResultsA fifth (21%) of babies with hearing loss had one or more UK risk factors whereas most (86%) had at least one US risk factor. False positives would be evident if US factors were used whereas the matched controls had no UK risk factors. Ten babies who at birth had no UK or US risk factors did not have any significant neonatal indicators identified in their records, one was ventilated for one day and two had a genetic anomaly.Conclusions and RelevanceCurrent risk factors for hearing loss we identified for follow-up in this high-risk group are highly specific for congenital hearing loss. UK risk factors were highly specific for hearing loss but not sensitive and conversely, US risk factors are sensitive but not specific so false positives would be recorded. A national study of neonatal indicators could provide the utility to test which combinations of risk factors provide high sensitivity without losing specificity.Key pointsCurrent risk factors listed in UK guidance were highly specific for congenital hearing loss but not sensitive meaning cases would be missed. US risk factors were more sensitive for hearing loss but not very specific indicating false positives would be made in this population.Neonates with hearing loss who wouldnothave been identified solely according to US or UK risk factors were born close to term and had few neonatal indicators identified.

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Interdisciplinary Approaches Suggested for Children With Multiple Hospital Referrals Presenting With Non-specific Conditions

et al. 2021

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Aims: To describe the care patterns of patients with repeated referrals to both mental and somatic specialist healthcare, and to study their diagnostic processes.Methods: In a previous register study patients aged 6–12 years referred to Haukeland University Hospital from 2013 to 2015, we found 922 children with at least three referrals including both somatic and mental health services. Of these, more than one in four (250) were randomly selected and observed from their first hospital episode ever and further after inclusion followed during their next three referrals or until July 2017. Data on referral patterns and diagnostics were collected from patient hospital records.Results: Mean number of referrals was 6.5 prior to inclusion and 4.2 in the follow-up period. At the end of the study period 15% of patients still had a non-specific diagnosis. During the follow-up period, more than half of the children were again referred across the border between somatic and mental healthcare.Conclusion: Very complex care patterns were found for these patients, who were repeatedly being referred and “crossing over” between mental and somatic healthcare. This indicates a need for more interdisciplinary-based approaches both within specialist care and between different care levels to broaden the perspective and achieve shorter time lag before reaching a diagnostic conclusion.Trial Registration: Data was obtained from Haukeland university hospital the patient registry system No. 2017/12470. Start of registration was April 1th 2017 and patients included was from 2013 to 15.

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Children with congenital hearing loss – a vulnerable group

Cited by 4 publications

References 17 publications

UK and US risk factors for hearing loss in neonatal intensive care unit infants

UK and US risk factors for hearing loss in neonatal intensive care unit infants

UK and US risk factors for hearing loss in neonatal intensive care unit infants

Interdisciplinary Approaches Suggested for Children With Multiple Hospital Referrals Presenting With Non-specific Conditions

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