Children of Diabetic Mothers Electrocardiographic Studies in the Newborn

Björklund, Stig-Ivar

doi:10.1111/j.1651-2227.1953.tb04095.x

Cited by 16 publications

(3 citation statements)

References 23 publications

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“…The observation of a relationship between heart volume and measures of cardiac function as assessed by ECG and the measure of cardiac stroke volume could indicate that "cardiomegaly" in this group of infants was of adaptive type. ECG abnormalities usually disappearing within the first 5 days have been reported in IDMs (17). In larger series of IDMs, however, Gellis & Hsia (18) found no ECG abnormalities.…”

Section: Resultsmentioning

confidence: 91%

Circulatory Adaptation in Newborn Infants of Strictly Controlled Diabetic Mothers

et al. 1982

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Possible relations between neonatal circulatory function and maternal diabetic control were investigated in 22 infants of strictly controlled diabetic mothers during the first 2 days after birth. Eleven infants were delivered vaginally (V) and 11 infants by elective cesarean section (S). Maternal diabetes was more severe in the latter group. Half of the infants had one or more episodes of neonatal morbidity although none presented symptomatic hypoglycemia. Plasma glucose FFA and C-peptide were measured at birth and 3-6 hours later together with skinfold thickness; heart size was determined by X-ray at 24-28 hours; stroke volume and cardiac output were repeatedly determined by transthoracic impedance and ECG. C-peptide at birth was higher in group S than in V. C-peptide in both groups were neither related to glucose or FFA nor to birthweight or skinfold thickness. Infants with neonatal complications including cardiomegaly had the highest C-peptide values. Skinfold was positively correlated to maternal pregnancy glucose level, birthweight percentile and infant heart volume. Mean values for stroke volume and cardiac output were similar in both groups and not different from normal controls when related to body weight. Heart volume and stroke volume were significantly related. ECG abnormalities were seen in 6 infants who showed cardiomegaly on X-ray. We suggest that the present finding of an association between elevated C-peptide concentration at birth and the occurrence of neonatal complications including cardiomegaly and ECG abnormalities could be the consequence of functional hyperinsulinism and that the cardiomegaly is of adaptive type.

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Section: Resultsmentioning

confidence: 91%

Circulatory Adaptation in Newborn Infants of Strictly Controlled Diabetic Mothers

et al. 1982

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“…According to Bjorklund (1953) the serum potassium of babies born to diabetic women is low, and he found 'suppression or sagging' of the S-T segment, pathological negative T and U waves and prolongation of the QT interval on their electrocardiograms, but no such changes in a control group. They existed whether the baby showed clinical disturbance or not, but in no abnormal baby was the E.C.G.…”

Section: Metabolic Abnormalities Of the Foetusmentioning

confidence: 99%

The Child of the Diabetic Woman

Farquhar¹

1959

Archives of Disease in Childhood

111

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“…Changes in th e electro card io g rap h ic p a tte r n o ccurring in co n ju n ctio n w ith n eo n atal d istress (asp h y x ia, etc.) h av e been described in som e rep o rts (2,3,4,5,6). T h e effect o f p re m a tu rity on th e electro card io g ram has been well d o cu m en ted in several stu d ies, p a rtic u la rly those o f Salm i and co-workers (7) a n d o f Ilubsher (8).…”

Section: B Y C a R L O S V A L L B O N A An D M U R D In A M D E S Mmentioning

confidence: 99%