Children Grow on the Ketogenic Diet

Vining, Eileen P.G.; Casey, Jane; McGrogan, Jane R.; Schwerdt, Pamela; Anand, Akash; Pyzik, Paula L.; Freeman, John M.

doi:10.1203/00006450-199904020-02070

Cited by 4 publications

(4 citation statements)

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“…Height/length assessment in the current patients showed significant increase in its value as well as the z score for age. This agrees with Vining and collaborators 30 who reported that children grew taller during the first year on KD. In contrast, Tagliabue et al 31 studied 18 refractory epileptic children and they found a non-significant difference in height after 6 months KD.…”

Section: Discussionsupporting

confidence: 92%

Ketogenic diet for epilepsy control and enhancement in adaptive behavior

El-Rashidy

Nassar

Shokair

et al. 2023

Sci Rep

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The Ketogenic Diet (KD) is gaining attention as a management line in childhood drug resistant epilepsy (DRE). The objective of this study was to highlight KD benefits for Ain Shams University (ASU) Children’s Hospital patients. This cross-sectional study included all patients at the Ketoclinic of ASU Children’s Hospital since it started. Anthropometric measurements and laboratory data were recorded. Chalfont severity score and daily frequency of epileptic attacks were used to evaluate KD efficacy. Vineland test was used to demonstrate the adaptive behavior of a selected group of patients. ASU Children’s Hospital Ketoclinic records included 143 patients. During KD therapy, the weight and height/length assessment showed significant increase with significant decrease in the severity of seizures and its frequency. There were no significant changes in the lipid profile of the patients. Vineland test showed significant improvement in the adaptive behavior in 65% of patients. The Ketoclinic data proves that KD is a tolerable, safe, and effective line of therapy for DRE in children without significant negative impact on their anthropometric measurements or lipid profile. Furthermore, the enhancement in adaptive behavior is a promising finding. It is prudent to recommend wider scale studies for longer duration to demonstrate additional cognitive benefits of KD in pediatric age group.

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Section: Discussionsupporting

confidence: 92%

Ketogenic diet for epilepsy control and enhancement in adaptive behavior

El-Rashidy

Nassar

Shokair

et al. 2023

Sci Rep

View full text Add to dashboard Cite

show abstract

“…Height/length assessment in the current patients showed signi cant increase in its value as well as the z score for age. This agrees with Vining and collaborators [29] who reported that children grew taller during the rst year on KD. In contrast, Tagliabue et al [30] studied 18 refractory epileptic children and they found a non-signi cant difference in height after 6 months KD.…”

Section: Discussionsupporting

confidence: 92%

Benefits of Ketogenic Diet Beyond Epilepsy Control: Promising Enhancement in Adaptive Behavior

El-Rashidy

Nassar

Shokair³

et al. 2022

Preprint

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Background The Ketogenic Diet (KD) is gaining attention as a management line in childhood drug resistant epilepsy (DRE). The objective of this study was to highlight KD benefits for Ain Shams University (ASU) Children’s Hospital patients. Methods This cross-sectional study included all patients at the Ketoclinic of ASU Children’s Hospital since its start. Anthropometric measurements and laboratory data were assessed. To evaluate KD efficacy, Chalfont severity score and daily frequency of epileptic attacks were recorded. Vineland test was used to demonstrate the adaptive behavior of a selected group of patients. Results The record of the Ketoclinic included 143 patients. Weight and height/length assessment showed significant increase with significant decrease in the severity of seizures and its frequency after KD. There were no significant changes in the lipid profile of the patients. Vineland test showed significant improvement in the adaptive behavior in 65%. Conclusions The Ketoclinic data proves that KD is a tolerable, safe, and effective line of therapy for DRE in children without significant negative impact on their anthropometric measurements or lipid profile. furthermore, the enhancement in adaptive behavior is a promising finding, thus it is prudent to recommend wider scale studies for longer duration to demonstrate additional cognitive benefits.

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“…Respecto a la evolución del estado nutricional, llama la atención el compromiso de la talla en el seguimiento a largo plazo (18 meses). En la literatura se ha descrito que el crecimiento lineal en los pacientes con DK puede ocurrir a una velocidad menor, pero normal 15 . Sin embargo, otros trabajos describen una disminución significativa en la relación talla/edad después de 6 meses en dieta 16,17 .…”

Section: Discussionunclassified

Dieta cetogénica en epilepsia refractaria: Eficacia, evolución y complicaciones a largo plazo

et al. 2007

Rev. chil. pediatr.

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Ketogenic Diet in Refractory Epilepsy: efficacy, evolution and long-term complicationsBackground: Ketogenic diet (KD) represents an alternative in treatment of refractory epilepsy (RE). Objective: To evaluate the efficacy of the diet and the frequency of complications in patients belonging to the KD Program from Luis Calvo Mackenna Children's Hospital (HLCM). Methods: Evaluation of all children enrolled in the program between 1999 and 2004, with analysis every 6 months of the diet efficacy, digestive tolerance, nutritional status, cholesterol levels and nephrolithiasis. Results: 21 children were admitted, 14 boys, age between 6 months -17 years-old. 76%, 71% and 67% of patients followed KD at 6, 12 and 18 months, respectively, with KD efficacy of 67%. At 12 months, 24% of patients did not present seizures. At 18 months, 85% remained close to ideal body weight (15% obesity) and height/age Z score decreased (-0,7 ± 0,4; p < 0,05). Total cholesterol significantly increased at 6 months (64% hypercholesterolemia; decreased to 15% at 18 months). 2 patients developed nephrolithiasis. Conclusions:The study shows high efficacy of the KD for treatment of refractory epilepsy, with low rate of complications. It should be considered as a therapeutic alternative for these patients. (

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Children Grow on the Ketogenic Diet

Cited by 4 publications

References 0 publications

Ketogenic diet for epilepsy control and enhancement in adaptive behavior

Ketogenic diet for epilepsy control and enhancement in adaptive behavior

Benefits of Ketogenic Diet Beyond Epilepsy Control: Promising Enhancement in Adaptive Behavior

Dieta cetogénica en epilepsia refractaria: Eficacia, evolución y complicaciones a largo plazo

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