Childhood tuberculosis in the Bronx, New York

Drucker, Ernest; Alcabes, Philip; Sckell, Blanca; Bosworth, William

doi:10.1016/s0140-6736(94)92588-7

Cited by 113 publications

(48 citation statements)

References 12 publications

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“…Drucker e colaboradores 10 , estudando crianças do Bronx com tuberculose, apontam a pobreza e aglomeração como potentes fatores de risco para tuberculose, mesmo controlando para AIDS. Por outro lado, cabe ressaltar alguns estudos em que tal associação não foi encontrada.…”

Section: Discussionunclassified

Incidência e fatores de risco para tuberculose em Pelotas, uma cidade do Sul do Brasil

Menezes

Costa²,

Gonçalves³

et al. 1998

Rev. bras. epidemiol.

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Objetivou-se medir a incidência e avaliar fatores de risco para tuberculose, em adultos de Pelotas. Os casos foram detectados na "Secretaria Municipal da Saúde e Bem Estar" (Centro de Saúde), no período de junho de 1994 a junho de 1995. Concomitante, controles populacionais, pareados por sexo e idade, eram sorteados e aplicado o mesmo questionário aos casos e controles. A incidência notificada de tuberculose foi de 72,4/100.000 habitantes. A análise estatística bruta mostrou os seguintes odds ratios: 10,8 (classe social E), 5,4 (renda familiar < 1 salário mínimo) e 6,6 (analfabetos). O risco em pessoas de cor não branca foi de 4,7; aglomeração e contato com tuberculose apresentaram respectivamente riscos de 3,1 e 5,3. Alcoolismo mostrou um risco de 4,3 e os portadores de doenças associadas à tuberculose um risco de 3,6; as variáveis história de diabete e moradia próxima a pedreiras não se mostraram associadas com tuberculose. Os trabalhadores de pedreiras apresentaram um risco de 4,0. Na análise por regressão logística condicional, as seguintes variáveis permaneceram, após ajuste para fatores de confusão, significativamente associadas com tuberculose: contato com tuberculose (OR=8,2), alcoolismo (OR=4,0), trabalho em pedreira (OR=4,7) e cor não branca (OR=3,1). Conclui-se que a incidência de tuberculose em Pelotas é muito elevada e que a maioria dos fatores de risco são passíveis de prevenção ou redução.

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Section: Discussionunclassified

Incidência e fatores de risco para tuberculose em Pelotas, uma cidade do Sul do Brasil

Menezes

Costa²,

Gonçalves³

et al. 1998

Rev. bras. epidemiol.

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“…Various international and Indian studies have found positive associations between overcrowding and poor ventilation with higher prevalence of TB. [8][9][10][11] In the present study, a considerable number of patients were exposed to inadequate ventilation [54 (46.1%)] while Overcrowding was not observed in the majority of the patients [6 (5.1%)].…”

Section: Resultsmentioning

confidence: 53%

Tobacco smoking trends and treatment outcomes in Tuberculosis patients of district Shimla, Himachal Pradesh, India: a cohort study

Singh

Thakur

Mazta³

et al. 2017

Int J Community Med Public Health

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Background: India carries the highest burden of tuberculosis worldwide. To achieve the goals of the ‘END TB’ strategy, it is imperative to understand the factors which can influence the treatment outcomes. The objectives were to study the socio-demographic characteristics of the subjects and to study the factors influencing treatment outcomes in the TB patients. Methods: A prospective cohort study design was employed and all patients (n=117) who were registered for category I DOTS during the last quarter of 2015 were included after obtaining written informed consent. Home visits with patient interviews were conducted to collect information on determinants. Univariate and binary logistic regression models were employed. Results: The overall treatment success rate was 93.2% (Cure rate=87%, treatment completion rate=100%). Default, death, failure and lost to follow up rates were 2.6%, 2.6%, 0.8% and 0.8% respectively. Those with a history of tobacco smoking [RR: 6 (1.27-28.37); p=0.02], second hand smoke [RR: 8.75 (1.11-68.88); p=0.02], indoor air pollution [RR: 7.89 (1.10-62.13); p=0.02] and alcohol use [RR: 6.13 (1.57-23.93); p=0.01] had higher risks of developing unfavourable treatment outcomes. The commonest cause of indoor air pollution was smoke surfacing out of fire-wood used for cooking and tobacco. Conclusions: The treatment success rates conform to the END TB strategy targets of 90%. Tobacco smoking, second hand smoke, indoor air pollution and alcohol intake were associated with adverse outcomes. Health education regarding the ill effects of tobacco and alcohol with regards to the disease preventability and curability needs to be further intensified. Larger studies to determine the effect of indoor air pollution as a risk factor and its impact on treatment outcomes by contemporary scientific methods by collaborating with other agencies involved in environmental studies is highly recommended.

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“…7 Various international and Indian studies have found positive associations between overcrowding and poor ventilation with higher prevalence of TB. 8,9,10,11 In the present study, a considerable number of patients were exposed to inadequate ventilation [54(46.1%)] while Overcrowding was not observed in the majority of the patients [6(5.1%)].…”

Section: Discussion:-mentioning

confidence: 53%

Indoor Air Pollution and Treatment Outcomes in Tb Patients of a Hiily District in North India.

Singh¹,

Thakur²,

Mazta³

et al. 2017

IJAR

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Background: India carries the highest burden of Tuberculosis in the world. For progression towards the goal of global elimination, it is imperative to understand the factors which influence the treatment outcomes. The objectives were to study the socio-demographic characteristics of the subjects and to study the factors influencing treatment outcomes in the TB patients. Methods: A Cross-sectional study design was employed and all patients (n=117) who were registered for Category I DOTS during the last quarter of 2015 were included after obtaining written informed consent. Patients were visited at their homes for interviews to note socio-demographic and environmental characteristics and secondary data analysis was done to note the outcomes. Univariate and binary logistic regression models were employed. Results: The overall treatment success rate was 93.2% (Cure rate= 87%, treatment completion rate= 100%). Default, death, failure and lost to follow up rates were 2.6%, 2.6%, 0.8% and 0.8% respectively. Those with a history of indoor air pollution [OR: 7.89 (1.10-62.13); p=0.02], tobacco smoking [OR: 6 (1.27-28.37); p=0.02], alcohol use [OR: 6.13 (1.57-23.93); p=0.01] and second hand smoke ); p=0.02] had higher odds of developing unfavourable treatment outcomes. The commonest cause of indoor air pollution was smoke surfacing out of fire-wood used for cooking and tobacco. Conclusion: The study observed air pollution due to firewood and tobacco smoke and alcohol intake to be associated with adverse outcomes. Health education regarding the ill effects of indoor air pollution and alcohol with regards to the disease preventability and curability needs to be further intensified. Larger studies are highly recommended to determine the effect of indoor air pollution as a risk factor and its impact on treatment outcomes by contemporary scientific methods.

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Childhood tuberculosis in the Bronx, New York

Cited by 113 publications

References 12 publications

Incidência e fatores de risco para tuberculose em Pelotas, uma cidade do Sul do Brasil

Incidência e fatores de risco para tuberculose em Pelotas, uma cidade do Sul do Brasil

Tobacco smoking trends and treatment outcomes in Tuberculosis patients of district Shimla, Himachal Pradesh, India: a cohort study

Indoor Air Pollution and Treatment Outcomes in Tb Patients of a Hiily District in North India.

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