Childhood Stress and Adversity is Associated with Late-Life Dementia in Aboriginal Australians

Radford, Kylie; Delbaere, Kim; Draper, Brian; Mack, Holly A.; Daylight, Gail; Cumming, Robert; Chalkley, Simon; Minogue, Cecilia; Broe, G. A.

doi:10.1016/j.jagp.2017.05.008

Cited by 121 publications

(112 citation statements)

References 39 publications

(62 reference statements)

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“…A growing number of studies regarding late-life cognition have concentrated on the effects of early-life and late-life factors, such as childhood deprivation and adversity, adult socioeconomic status (SES), and lifestyles. [9][10][11][12] Childhood SES is a powerful predictor of health outcomes in later life, always measured by the parental education and occupation or household income. Recently, emerging data have indicated that both higher childhood and adult SES can prevent poor cognitive function in later-life.…”

Section: Introductionmentioning

confidence: 99%

Associations of childhood socioeconomic status with mid‐life and late‐life cognition in Chinese middle‐aged and older population based on a 5‐year period cohort study

Sha

Cheng

2018

Int J Geriat Psychiatry

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ObjectivesA prospective study was performed to examine the relationship of childhood socioeconomic status (SES) with cognition and the rate of change in a nationally representative sample of community‐dwelling middle‐aged and older Chinese population.MethodsThis study mainly focused on 3 composite measures of cognitive function, including Telephone Interview of Cognitive Status, word recall, and drawing a figure successfully. Childhood SES was evaluated by parental occupation and education, childhood residence, and self‐evaluated financial status. We designed an analysis strategy adding predictors incrementally in different models to examine the changes of effects of childhood SES on cognition by latent growth curve models.ResultsFinally, a total of 10 533 respondents were prospectively studied, including 5980 respondents aged 45–59 and 4553 aged 60–90. Cognition in younger cohort showed a curvilinear change, while cognition in older cohort showed a linear decline. After controlling for covariates, middle‐aged respondents with higher self‐evaluated financial status (β: −0.22, P < .001), better health status (β: −0.13, P < .001), higher parental education (β: 0.17 and 0.10, P < .001), who had lived in city/town before 16 years (β: 0.69, P < .001), and whose fathers engaged in nonfarming work (β: 0.43, P < .001) were associated with the better baseline cognition. Similar results were found in older cohort. Additionally, early‐life SES was not associated with cognitive decline in both cohorts.ConclusionsThis study indicates that childhood SES is associated with mid‐life and late‐life baseline cognition, but it is not contributed to cognition decline. Interventions in early‐life focused on improving childhood SES might have positive impacts on baseline cognition in later‐life.

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Section: Introductionmentioning

confidence: 99%

Associations of childhood socioeconomic status with mid‐life and late‐life cognition in Chinese middle‐aged and older population based on a 5‐year period cohort study

Sha

Cheng

2018

Int J Geriat Psychiatry

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“…Marital violence in the past may be an associated feature, but this needs further investigation. Post‐traumatic stress disorder, even during infancy, may be a risk factor for dementia …”

Section: Discussionmentioning

confidence: 62%

“…Post-traumatic stress disorder, even during infancy, may be a risk factor for dementia. 26,27 The inhibited temperament (BI), as in our patient, is a vulnerability factor for anxiety disorders [28][29][30][31][32][33] similar to the intolerance of uncertainty. 34 Vocally disruptive behaviour may be related to an underlying premorbid psychiatric disorder.…”

Section: Phenomenologymentioning

confidence: 99%

Phenomenological contribution to understanding of vocally disruptive behaviour: A clinical case study in a patient with dementia

Tible¹,

Mendez²,

Gunten³

2018

Int J Geriat Psychiatry

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Phenomenology in vocally disruptive behaviour in dementia. We have found new explanations in similar clinical cases in dementia as follows. A patient presenting with vocally disruptive behaviour has a melancholic type, a behavioural-inhibited temperament, and marital violence in the past. Phenomenology may help explain this profile with neurobiological disorders. The life trajectory, from childhood into older age, must be taken into account to understand behavioural and psychological symptoms of dementia.

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“…Moreover, MT and conjugal violence were found several times, during the life history. Or, Post-Traumatic Stress Disorder is probably a risk of dementia, even if it appears in infancy [26,27]. The inhibited temperament (BI) is also found by the entourage's interview (significant timidity, and inhibition, and anxiety or discomfort in new social situations are found).…”

Section: Big Five Dimensionsmentioning

confidence: 99%

Phenomenological Understanding of Behavioural and Psychological Symptoms of Dementia: A Clinical Case Presenting Howls and Shouting. The Melancholic Type and Phenomenology of Separation

Tible¹,

Mendez²,

Gunten³

2017

J Depress Anxiety

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Childhood Stress and Adversity is Associated with Late-Life Dementia in Aboriginal Australians

Cited by 121 publications

References 39 publications

Associations of childhood socioeconomic status with mid‐life and late‐life cognition in Chinese middle‐aged and older population based on a 5‐year period cohort study

Associations of childhood socioeconomic status with mid‐life and late‐life cognition in Chinese middle‐aged and older population based on a 5‐year period cohort study

Phenomenological contribution to understanding of vocally disruptive behaviour: A clinical case study in a patient with dementia

Phenomenological Understanding of Behavioural and Psychological Symptoms of Dementia: A Clinical Case Presenting Howls and Shouting. The Melancholic Type and Phenomenology of Separation

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