Childhood microbial keratitis

Otaibi, Abdullah G Al; Allam, Khalid; Damri, Al Johara; Shamri, Aysha Al; Kalantan, Hatem; Mousa, Ahmed

doi:10.4103/0974-620x.94763

Cited by 21 publications

(45 citation statements)

References 16 publications

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“…Comorbidities were present in 5.8% of the study patients; this was lower than rates reported in previous studies (3,(8)(9)(10)(11)(12)(13)(14) . Cancer was the main comorbidity, present in 2% of our records.…”

Section: Discussioncontrasting

confidence: 51%

“…The prevalence of microorganisms responsible for microbial ke ratitis in children and adolescents varies in different regions of the world (3) . Microbial cultures were positive in 40.3% of the study sample, whereas in the literature positivity has ranged from 33% to 87% (3,(8)(9)(10)(12)(13)(14)(15)(16)(17)(18)20,29) . Polymicrobial isolates accounted for 9.5% of positive cultures in our study.…”

Section: Discussionmentioning

confidence: 85%

“…As has been said, the association between the use of contact lenses and infectious ulcers is well esta blished. Several authors have reported the use of contact lenses, es pecially orthokeratology, as a predisposing factor for keratitis in chil dren and adolescents (3,(8)(9)(10)14,17,19,20,30) . The use of this type of lens is not common in Brazil.…”

Section: Discussionmentioning

confidence: 99%

“…Trauma has been reported as the major risk factor for keratitis in several published studies, accounting for 21.2% to 58.8% of cases (8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)29) . In our study, 18.2% of patients had a history of using contact lenses.…”

Section: Discussionmentioning

confidence: 99%

“…(4)(5)(6)(7) . Infectious keratitis are more prevalent in tropical developing countries with poor healthcare systems than in developed countries (3,(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21) . The diagnosis of keratitis is usually clinical and the treatment is empirical, with the application of broad-spectrum topical antimicrobial agents until identification of the etiologic agent is completed.…”

mentioning

confidence: 99%

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Microbiological and epidemiological study of infectious keratitis in children and adolescents

Yu¹,

Höfling-Lima²,

Furtado³

2016

Arquivos Brasileiros De Oftalmologia

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Purpose: To analyze epidemiological and microbiological aspects of microbial keratitis in children and adolescents. Methods: This retrospective cohort study was conducted at the Department of Ophthalmology and Visual Science, Escola Paulista de Medicina, Universidade Federal de São Paulo, between July 15, 1975, and December 31, 2010. We analyzed corneal samples from 859 patients with clinical suspicion of infectious keratitis, comparing epidemiological and microbiological characteristics of bacterial keratitis with those of non-bacterial and non-viral keratitis. We also compared Gram-positive and Gram-negative pathogens in patients with bacterial keratitis. We created a susceptibility profile of the bacterial microorganisms studied. Results: Of the 859 patients, 346 (40.3%) showed positive culture results for non-viral microorganisms. Teenagers (13-18 years) made up the group with the highest number of patients with keratitis (164, 47.4%). The most frequent risk factors for keratitis were trauma (33.5%) and previous ocular surgery (24.9%). Gram-positive bacteria (71.8%) were the most often isolated, with coagulase-negative Staphylococcus (23.8%) the most prevalent microorganism. Logistic regression analysis showed age (p=0.002), topical antimicrobial drug use (p=0.01), and trauma due to non-chemical burns (p=0.005) were risk factors for non-bacterial keratitis. Age (p=0.01) was also a risk factor for Gram-negative bacterial keratitis. Conclusion: Our study showed that in the age range studied, the prevalence of keratitis caused by Gram-negative bacteria or by the non-viral microorganisms evaluated increases with age. Previous use of topical antimicrobial drug and trauma due to non-chemical burns are associated with non-bacterial keratitis. Knowledge of the risk factors and the microorganisms involved may help improve treatment of keratitis in children and adolescents and minimize visual impairment. (4)(5)(6)(7) . Infectious keratitis are more prevalent in tropical developing countries with poor healthcare systems than in developed countries (3,(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21) . The diagnosis of keratitis is usually clinical and the treatment is empirical, with the application of broad-spectrum topical antimicrobial agents until identification of the etiologic agent is completed. However, few studies have investigated the causative agents and risk factors of infectious keratitis in children and adolescents. KeywordsThe purpose of this study was to investigate the epidemiological and microbiological findings of infectious keratitis in patients up to 18 years of age attending a tertiary referral center. In addition, the Microbiological and epidemiological study of infectious keratitis in children and adolescentsEstudo microbiológico e epidemiológico da ceratite infecciosa em crianças e adolescentes Microbiological a n d e p i d e M i o l o g i c a l s t u d y o f i n f e c t i o u s k e r at i t i s i n c h i l d r e n a n d a d o l e s c e n t METHODSThis retrospective cohort study assessed...

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