Childhood maltreatment and its impact on the mental health

Sivolap, Yu P; Portnova, Anna A.

doi:10.17116/jnevro201611671108-112

Cited by 3 publications

(1 citation statement)

References 36 publications

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“…Finally, in this study, we focused on the association between subcortical structures, childhood trauma and perceived stress in schizophrenia. Childhood trauma has been reported in many mental disorders (Sivolap & Portnova, 2016), including depression (Aghamohammadi-Sereshki et al, 2021), bipolar disorders (Janiri et al, 2017), as well as alcohol use (Phillips et al, 2021). It is worth exploring in future studies whether the effect of trauma is independent of diagnosis or if diagnosis specificity is present.…”

Section: Discussionmentioning

confidence: 99%

Subcortical structures associated with childhood trauma and perceived stress in schizophrenia

et al. 2022

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Background Childhood trauma influences the clinical features of schizophrenia. In this study, we examined how childhood trauma and perceived stress are associated with clinical manifestations and subcortical gray matter volumes (GMVs) in patients with schizophrenia. Methods We recruited 127 patients with schizophrenia and 83 healthy controls for assessment of early childhood trauma, perceived stress, and clinical symptoms. With structural brain imaging, we identified the GMVs of subcortical structures and examined the relationships between childhood trauma, perceived stress, clinical symptoms, and subcortical GMVs. Results Compared to controls, patients with schizophrenia showed higher levels of childhood trauma and perceived stress. Patients with schizophrenia showed significantly smaller amygdala and hippocampus GMVs as well as total cortical GMVs than age-matched controls. Childhood trauma score was significantly correlated with the severity of clinical symptoms, depression, perceived stress, and amygdala GMVs. Perceived stress was significantly correlated with clinical symptoms, depression, and hippocampus and amygdala GMVs. Further, the association between childhood trauma (emotional neglect) and stress coping ability was mediated by right amygdala GMV in patients with schizophrenia. Conclusions Patients with schizophrenia had more exposure to early-life trauma and poorer stress coping. Both childhood trauma and perceived stress were associated with smaller amygdala volumes. The relationship between early-life trauma and perceived stress was mediated by right amygdala GMV in patients with schizophrenia. These findings together suggest the long-term effects of childhood trauma on perceived stress and the subcortical volumetric correlates of the effects in schizophrenia.

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Section: Discussionmentioning

confidence: 99%

Subcortical structures associated with childhood trauma and perceived stress in schizophrenia

et al. 2022

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Trajetórias sociais e vulnerabilidades associadas ao uso de crack e outras drogas: um estudo na cidade de São Paulo, Brasil

Reichert,

Ramos de Oliveira,

De Micheli

et al. 2023

culturaydroga

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Para atender às demandas de pessoas com necessidades relacionadas ao uso de substâncias psicoativas inseridas em contextos de vulnerabilidade social, são necessárias análises multinível para identificar aspectos relevantes nos quais devem intervir as políticas e programas de prevenção, redução de danos e tratamento. Em vista disso, este estudo objetivou caracterizar o perfil de usuários de substâncias psicoativas, analisar suas trajetórias sociais e identificar vulnerabilidades associadas ao uso de álcool, crack e outras drogas no centro da cidade de São Paulo (São Paulo, Brasil), na região popularmente conhecida como “Cracolândia”. Tratouse de um estudo de delineamento descritivo-exploratório e de métodos mistos, incluindo dados predominantemente qualitativos, cuja amostra foi composta por 35 participantes. Os dados foram analisados através de metodologia descritiva e análise de conteúdo. A partir dos resultados, verificou-se que essa população está exposta a uma série de vulnerabilidades individuais e processos de vulnerações sociais e político-institucionais, como exclusão nos campos educacional e profissional, afastamento da família e da comunidade, situação de rua, acesso limitado a serviços socioassistenciais, entre outras situações de violência e violações de direitos que podem levar ao uso radical de drogas. No contexto de vida dos usuários, o consumo de drogas mostrou-se associado ao enfrentamento das condições adversas de vida. Espera-se que esses dados possam subsidiar intervenções e políticas públicas sociais e de saúde amplas, integrativas, humanizadas e bioéticas voltadas a esse público.

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The Influence of Adverse Childhood Experiences on Mental Health: A Review Study

Sasidharan

2023

IJHSP

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Purpose: Adverse Childhood Experiences (ACEs) are a group of distressing and traumatic occurrences that occur during a person's early years, such as abuse, neglect, family problems, or violent interactions. Regardless of whether they occur throughout a person's developmental stage, these occurrences can have a long-term and negative impact on an individual's emotional well-being and general health. This study investigates the profound connection between early hardship and an individual's mental health. This scholarly review conducts a comprehensive examination of the objectives that support its research endeavour. In addition, this research will offer insight on the complex nature of ACEs and their significant influence on mental well-being consequences. Design: The material for this study was gathered from a variety of secondary sources, including journals, book chapters, conference proceedings, and other online sites. The body of research has been thoroughly examined and summarized. It is also used to identify the research objectives and gaps in the field. Findings: This meta-analysis investigates the multi-faceted connections between adverse childhood experiences and mental health. It underlines the critical need for interdisciplinary efforts to address ACEs and their effects on mental health, calling for early intervention and support networks to break the cycle of adversity and develop mental health resilience among affected persons. Originality/Value: This study examines current literature and incorporates secondary data acquired from a variety of online resources, such as research journals, technical book chapters, conference papers, and a few websites. All the articles selected were recent, from respected publications, and pertinent to the planned task. A concerted effort is made to select a study topic and carry out the research. Paper type: Review paper

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Childhood maltreatment and its impact on the mental health

Cited by 3 publications

References 36 publications

Subcortical structures associated with childhood trauma and perceived stress in schizophrenia

Subcortical structures associated with childhood trauma and perceived stress in schizophrenia

Trajetórias sociais e vulnerabilidades associadas ao uso de crack e outras drogas: um estudo na cidade de São Paulo, Brasil

The Influence of Adverse Childhood Experiences on Mental Health: A Review Study

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