Childhood catatonia, autism and psychosis past and present: is there an ‘iron triangle’?

Shorter, Edward; Wachtel, Lee E.

doi:10.1111/acps.12082

Cited by 51 publications

(17 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Both patients with ASD and those with schizophrenia can show odd mannerisms, stereotyped behaviours and a rigid, inflexible pattern of thinking and behaving (Delahunty 1993; Ridley 1994; Leung 2014). Catatonia has been described as a common endophenotype for both ASD and schizophrenia and there are descriptions of children presenting with mixed forms of catatonia, autistic and psychotic symptoms (Shorter 2013).…”

Section: Boundaries and Overlapsmentioning

confidence: 99%

Autism spectrum disorder and schizophrenia: boundaries and uncertainties

Pina‐Camacho¹,

Parellada²,

Kyriakopoulos³

2016

BJPsych advances

View full text Add to dashboard Cite

SummaryAutism and schizophrenia were placed in different diagnostic categories in DSM-III, having previously been considered as related diagnostic entities. New evidence suggests that these disorders show clinical and cognitive deficit overlaps and shared neurobiological characteristics. Furthermore, children presenting with both autism spectrum disorder (ASD) and psychotic experiences may represent a subgroup of ASD more closely linked to psychosis. The study of ASD and childhood schizophrenia, and their clinical boundaries and overlapping pathophysiological characteristics, may clarify their relationship and lead to more effective interventions. This article discusses the relationship through a critical review of current and historical dilemmas surrounding the phenomenology and pathophysiology of these disorders. It provides a framework for working with children and young people with mixed clinical presentations, illustrated by three brief fictional case vignettes.

show abstract

Section: Boundaries and Overlapsmentioning

confidence: 99%

Autism spectrum disorder and schizophrenia: boundaries and uncertainties

Pina‐Camacho¹,

Parellada²,

Kyriakopoulos³

2016

BJPsych advances

View full text Add to dashboard Cite

show abstract

“…As shown in our review, they may bring into question the possibility of mixed and overlapping illness states. Although this approach is at odds with the traditional concept of classifying mental health disorders into single categories, our review provides a prototypical example that some symptoms may not be assigned to one specific diagnostic category, but instead tap a number of diagnostic categories that overlap in terms of symptoms and thus must be considered against the background of this spectrum [60]. This is the case specifically in adolescents who commonly present phenomena that theoretically not only span a large diagnostic spectrum, but often lie on a continuum from normal adolescent to actual pathological states, including attenuated or established psychosis.…”

Section: Discussionmentioning

confidence: 99%

Cenesthopathy in adolescence: An appraisal of diagnostic overlaps along the anxiety–hypochondriasis–psychosis spectrum

Simon

Borgwardt

Lang

et al. 2014

Comprehensive Psychiatry

View full text Add to dashboard Cite

Objective: To discuss the diagnostic validity of unusual bodily perceptions along the spectrum from age-specific, often transitory and normal, to pathological phenomena in adolescence to hypochondriasis and finally to psychosis. Methods: Critical literature review of the cornerstone diagnostic groups along the spectrum embracing anxiety and cenesthopathy in adolescence, hypochondriasis, and cenesthopathy and psychosis, followed by a discussion of the diagnostic overlaps along this spectrum. Results: The review highlights significant overlaps between the diagnostic cornerstones. It is apparent that adolescents with unusual bodily perceptions may conceptually qualify for more than one diagnostic group along the spectrum. To determine whether cenesthopathies in adolescence mirror emerging psychosis, a number of issues need to be considered, i.e. age and mode of onset, gender, level of functioning and drug use. The role of overvalued ideas at the border between hypochondriasis and psychosis must be considered. Conclusion: As unusual bodily symptoms may in some instances meet formal psychosis risk criteria, a narrow understanding of these symptoms may lead to both inappropriate application of the new DSM-5 attenuated psychosis syndrome and of treatment selection. On the other hand, the possibility of a psychotic dimension of unusual bodily symptoms in adolescents must always be considered as most severe expression of the cenesthopathy spectrum. We would like to thank the reviewer for raising this important point. As we did not follow specific guidelines "Preferred Reporting Items for Systematic Reviews and Meta-Analyses" (PRISMA) guidelines (Moher et al., 2009), we agree with your comment that this a selective and not systematic review. Therefore, we now removed the term "systematic" and clearly state that this is a "critical" review. Furthermore, we have rephrased the methods in more detail on page 4, line 21, to page 5, line 9. We also acknowledge that including a discussion of somatization is an important aspect. This now features on page 9, lines 3 to 19. We did not include a discussion of the Briquet"s syndrome. This is a specific somatization disorder with multiple symptoms, and our above mentioned paragraph includes the general concept of somatization, thus also Briquet"s syndrome. We however now included the concept of somatic delusions in our section on "cenesthopathy and psychosis" that we have restructured substantially (see page 12, lines 13 to 24). We now also reference somatic delusions on page 16, line 7 (references 52 and 53). The main conclusion of the paper is that there is the risk that the DSM-5 attenuated psychosis syndrome may be over-diagnosed given the fact that unusual body experiences seem to be an aspecific feature of several disorders not only psychosis. I did not find a solid argument for this conclusion in the discussion. Also could the authors offer any suggestions to avoid this problem of overdiagnosis and propose alternate methods of assessment and appraisal of distortions ...

show abstract

“…When a single diagnosis such as "schizophrenia" is given, the standard treatments may prove markedly ineffective (Shorter and Wachtel, 2013).…”

Section: Impact Of Developmental Disorders (Idd and Asd) In The Diagnmentioning

confidence: 99%

The diagnostic boundary between autism spectrum disorder, intellectual developmental disorder and schizophrenia spectrum disorders

Bertelli¹,

Merli²,

Bradley

et al. 2015

Advances in Mental Health and Intellectual Disabilities

View full text Add to dashboard Cite

Purpose – During the last few years the prevalence of autism and Autism Spectrum Disorder (ASD) has increased greatly. A recurring issue is the overlap and boundaries between Intellectual Developmental Disorder (IDD), ASD and Schizophrenia Spectrum Disorders (SSD). In clinical practice with people with IDD, the alternative or adjunctive diagnosis of ASD or SSD is particularly challenging. The purpose of this paper is to define the boundaries and overlapping clinical characteristics of IDD, ASD and SSD; highlight the most relevant differences in clinical presentation; and provide a clinical framework within which to recognize the impact of IDD and ASD in the diagnosis of SSD. Design/methodology/approach – A systematic mapping of the international literature was conducted on the basis of the following questions: first, what are considered to be core and overlapping aspects of IDD, ASD and SSD; second, what are the main issues in clinical practice; and third, can key diagnostic flags be identified to assist in differentiating between the three diagnostic categories? Findings – Crucial clinical aspects for the differentiation resulted to be age of onset, interest towards others, main positive symptoms, and anatomical anomalies of the central nervous system. More robust diagnostic criteria and semeiological references are desirable. Originality/value – The present literature mapping provides a comprehensive description of the most relevant differences in the clinical presentation of ASD and SSD in persons with IDD.

show abstract

Childhood catatonia, autism and psychosis past and present: is there an ‘iron triangle’?

Cited by 51 publications

References 34 publications

Autism spectrum disorder and schizophrenia: boundaries and uncertainties

Autism spectrum disorder and schizophrenia: boundaries and uncertainties

Cenesthopathy in adolescence: An appraisal of diagnostic overlaps along the anxiety–hypochondriasis–psychosis spectrum

The diagnostic boundary between autism spectrum disorder, intellectual developmental disorder and schizophrenia spectrum disorders

Contact Info

Product

Resources

About