Childhood cancers and the immune system

Stewart, Alice

doi:10.1007/bf00199522

Cited by 5 publications

(2 citation statements)

References 19 publications

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“…Although the cause of this observed increase has not been determined, etiologic hypotheses include exposure to new environmental agents and the appearance of ALL in patients who would have died of infections during a preleukemic period in earlier years when antibiotics were not available [29,30]. In contrast, other studies have not found such increases.…”

Section: Discussionmentioning

confidence: 81%

“…The incidence of acute lymphocytic leukemia in males aged 0-4 years has more than tripled over the time period increasing incidence of ALL in males aged 0-4 years and females aged 0-9 years [13]. Although the cause of this observed increase has not been determined, etiologic hypotheses include exposure to new environmental agents and the appearance of ALL in patients who would have died of infections during a preleukemic period in earlier years when antibiotics were not available [29,30]. In contrast, other studies have not found such increases.…”

Section: Discussionmentioning

confidence: 99%

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Trends in the incidence of childhood and adolescent cancer in connecticut, 1935–1979

Hoff

Schymura

Curnen

1988

Med. Pediatr. Oncol.

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Trends in the incidence of childhood cancer in Connecticut are reported and analyzed for the period 1935-1979 by 5-year age groups (0-4,5-9,lO-14,15-I9 years), using a log linear model method. A threefold increase (P < .001) in the incidence of ALL in males 0-4 years of age was observed, with significant increases of smaller magnitude seen in males aged 5-9 and 15-19 and females aged 0-4 and 5-9. The incidence of central nervous system cancers also increased in several age groups for both sexes with the largest increase seen in males 0-4 years old. Significant increases in incidence of large magnitude were also observed

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Section: Discussionmentioning

confidence: 81%

Section: Discussionmentioning

confidence: 99%