Childhood Bullous Pemphigoid: Report of a Case with Life‐Threatening Course During Homeopathy Treatment

Kuenzli, Stéphane; Grimaître, M.; Krischer, Joachim; Saurat, Jean‐Hilaire; Calza, Anne‐Marie; Borradori, Luca

doi:10.1111/j.0736-8046.2004.21215.x

Cited by 39 publications

(35 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is important with regard to patient safety that homeopaths do not ignore signs of serious adverse effects (red flag situations) and thus provoke a dangerous situation for the patients. Consequences of overlooking serious symptoms are demonstrated in the case presented previously [4] and in a systematic review recently published [28]. …”

Section: Risk Assessment and Patient Safetymentioning

confidence: 91%

“…Data from observational studies and surveys [24] reveal that reported adverse effects from homeopathic treatment fluctuate between 2 and 11% [25]. Several cases published in scientific literature confirm these findings [4,26,27]. A review of case reports published in 2012 [28] reported that among the 38 primary cases included, 30 pertained to direct adverse effects of homeopathic remedies of different potencies and another 8 were related to adverse effects caused by substituting homeopathy for conventional medicine.…”

Section: Risk Assessment and Patient Safetymentioning

confidence: 97%

“…A severe example from homeopathic treatment in which the ethical dictum to do no harm was heavily violated, was a case where a 9-month-old baby was admitted to hospital after homeopathic treatment [4]. She had been given several homeopathic remedies of different potencies to treat atopic dermatitis.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

How to Handle Worsening of Condition during Treatment - Risk Assessment in Homeopathic Practice

Salamonsen¹,

Kristoffersen²

2015

Complement Med Res

View full text Add to dashboard Cite

Even though homeopathy is regarded as a harmless intervention, homeopathic practice may not be entirely risk-free. Risk in homeopathy can be divided into direct and indirect risk. Direct risk refers to traditional adverse effects of an intervention; indirect risk is related to adverse effects in a treatment context, e.g. the practitioner. Available data suggest that the risk profile of homeopathic remedies in ultra-molecular potencies is minor, but there is a potential for indirect risk related to homeopathic practice. The concept of ‘homeopathic aggravation' which is unique for homeopathy may impose a particular risk as it allows the health status of the patients to deteriorate before there is a possible improvement. In that respect it is imperative to distinguish homeopathic aggravations from adverse effects. In a general risk evaluation of the homeopathic treatment it may be useful to assess the patient's symptoms in accordance with the natural course of disease and to evaluate any negative deviation from the normal curve as a possible adverse effect of the treatment. It is imperative that more emphasis is placed on patient safety during the education in homeopathy, and that students are trained to identify serious and red flag situations.

show abstract

Section: Risk Assessment and Patient Safetymentioning

confidence: 91%

Section: Risk Assessment and Patient Safetymentioning

confidence: 97%

See 1 more Smart Citation

How to Handle Worsening of Condition during Treatment - Risk Assessment in Homeopathic Practice

Salamonsen¹,

Kristoffersen²

2015

Complement Med Res

View full text Add to dashboard Cite

show abstract

“…We are not aware of a high prevalence of atopy in BP patients, although there is a report of BP in an atopic girl on homeopathic therapy [13] . In our patient, the persistently elevated IgE levels that had already been detected 23 years before the appearance of BP are probably more related to atopy than to BP.…”

Section: Introductionmentioning

confidence: 90%

Bullous Pemphigoid in a Patient with Netherton’s Syndrome

Barnadas

Gelpí²,

Agustí³

et al. 2007

Dermatology

View full text Add to dashboard Cite

“…In one case (28), a nine-month old baby girl was given several homeopathic remedies to treat atopic dermatitis. The child developed Bullous Pemphigoid (BP) during the treatment period and when the baby was finally admitted to the hospital, the condition was life threatening.…”

Section: Introductionmentioning

confidence: 99%

Adverse effects of homeopathy, what do we know? A systematic review and meta-analysis of randomized controlled trials

Kristoffersen

Alræk

Liu

2016

Complementary Therapies in Medicine

View full text Add to dashboard Cite

Highlights:• This review address the naive assumption that because of the generally diluted doses used homeopathy must be safe• This review touches the neglected issue of the distinction between homeopathic aggravation, adverse reactions and adverse effects• We found a similar risk for homeopathic treatment compared to controls such as placebo and conventional medicine. Words: 5,187 Abstract ObjectivesHomeopathy is a popular treatment modality among patient, however there is sparse research about adverse effects of homeopathy. A concept unique for homeopathy, is homeopathic aggravation that is understood as a transient worsening of the patients' symptoms before an 2 expected improvement occurs. From a risk perspective it is vital that a distinction between homeopathic aggravations and adverse effects is established. There is a lack of systematic information on how frequent adverse effects and homeopathic aggravations are reported in studies. Therefore, a systematic review and meta-analysis were performed. Design and settingSixteen electronic databases were searched for Randomized Controlled Trials (RCTs). The searches were limited from the year 1995 to January 2011. Forty-one RCTs, with a total of 6.055 participants were included. A subtotal of 39 studies was included in the additional metaanalysis. ResultsA total of 28 trials (68%) reported adverse effects and five trials (12%) reported homeopathic aggravations. The meta-analysis (including six subgroup comparisons) demonstrated that no significant difference was found between homeopathy and control with OR 0.99, 95% CI 0.86 to 1.14, I 2 = 54%. More than two third of the adverse effects were classified as grade 1 (68%) and two third were classified as grade 2 (25%) and grade 3 (6%) according to the Common Terminology Criteria for Adverse Effects. Homeopathic aggravation was classified as grade 1 (98%) and grade 3 (2%), suggesting that homeopathic aggravations were reported to be less severe than adverse effects. The methodological quality according to a method recommended in the Cochrane handbook for RCTs, was high. ConclusionAdverse effects including the concept of homeopathic aggravations are commonly reported in trials. The meta-analysis demonstrated that the proportion of patients experiencing adverse effects to be similar for patients randomized to homeopathic treatment compared to patients randomized to placebo and conventional medicine.

show abstract

Childhood Bullous Pemphigoid: Report of a Case with Life‐Threatening Course During Homeopathy Treatment

Cited by 39 publications

References 30 publications

How to Handle Worsening of Condition during Treatment - Risk Assessment in Homeopathic Practice

How to Handle Worsening of Condition during Treatment - Risk Assessment in Homeopathic Practice

Bullous Pemphigoid in a Patient with Netherton’s Syndrome

Adverse effects of homeopathy, what do we know? A systematic review and meta-analysis of randomized controlled trials

Contact Info

Product

Resources

About