Childhood betrayal trauma, dissociation, and shame impact health-related quality of life among individuals with chronic pelvic pain

Panisch, Lisa S.; Rogers, Rebecca G.; Breen, Michael T.; Nutt, Stephanie; Dahud, Soraya; Salazar, Christina

doi:10.1016/j.chiabu.2022.105744

Cited by 5 publications

(1 citation statement)

References 57 publications

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“…The compounding effects of distress generated by gender dysphoria is also reflected in the high incidence of suicide and disabling behavioral syndromes in transgender individuals in whom the dysphoria is not addressed ( 4 , 9 , 10 ). As will be reviewed below, it is widely appreciated in many human conditions that such unmitigated stressors can lead to profound exacerbations of pain phenotypes ( 11 , 12 ) and this may have a strong sex/gender component ( 13 , 14 ).…”

Section: Introductionmentioning

confidence: 99%

Pain mechanisms in the transgender individual: a review

Anger,

Case,

Baranowski

et al. 2024

Front. Pain Res.

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Specific AimProvide an overview of the literature addressing major areas pertinent to pain in transgender persons and to identify areas of primary relevance for future research.MethodsA team of scholars that have previously published on different areas of related research met periodically though zoom conferencing between April 2021 and February 2023 to discuss relevant literature with the goal of providing an overview on the incidence, phenotype, and mechanisms of pain in transgender patients. Review sections were written after gathering information from systematic literature searches of published or publicly available electronic literature to be compiled for publication as part of a topical series on gender and pain in the Frontiers in Pain Research.ResultsWhile transgender individuals represent a significant and increasingly visible component of the population, many researchers and clinicians are not well informed about the diversity in gender identity, physiology, hormonal status, and gender-affirming medical procedures utilized by transgender and other gender diverse patients. Transgender and cisgender people present with many of the same medical concerns, but research and treatment of these medical needs must reflect an appreciation of how differences in sex, gender, gender-affirming medical procedures, and minoritized status impact pain.ConclusionsWhile significant advances have occurred in our appreciation of pain, the review indicates the need to support more targeted research on treatment and prevention of pain in transgender individuals. This is particularly relevant both for gender-affirming medical interventions and related medical care. Of particular importance is the need for large long-term follow-up studies to ascertain best practices for such procedures. A multi-disciplinary approach with personalized interventions is of particular importance to move forward.

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