Child with unusual combination of sickle cell disease and autosomal recessive agammaglobulinemia associated with a novelCD79agene mutation

Abstract

This article describes a novel mutation in CD79a gene identified in a child with sickle cell disease (SCD), who was diagnosed with autosomal recessive agammaglobulinaemia in the context of prolonged febrile syndrome. The association of a primary immunodeficiency with SCD in the same child was unexpected.