Child Versus Adult Randomized Controlled Trials: a Citation Analysis of Trends, 1985–2005

Disease burden‐research match? Registered trials in child health from low‐ and middle‐income and high‐income countries

“…Our finding that there are fewer registered trials in children compared to adults has been extensively highlighted over the last decade . However, we observed that the gap is increasing and there are now approximately five times more trials in adults compared to children, with the number of trials in children plateauing.…”

StaR Child Health: Developing Evidence-Based Guidance for the Design, Conduct, and Reporting of Pediatric Trials

“…The summit was held on the eve of the twentieth anniversary of the adoption of the United Nations Convention on the Rights of the Child, which recognizes the right of all children to “the enjoyment of the highest attainable standard of health.” 1 Impediments to achieving this universal right are the paucity and well‐documented shortcomings of pediatric research and, more specifically, of clinical trials 2 . It is recognized that the quantity, quality, and relevance of data involving children are substantially lower than those involving adults 3 , 4 , 5 . This is despite data demonstrating that inadequate testing of interventions in children can result in ineffective or harmful treatments being offered or beneficial treatments being withheld 6 …”

An Adaptation of the Original Fresno Test to Measure Evidence‐Based Practice Competence in Pediatric Bedside Nurses

“…Although substantial research shows that when nurses use EBP, the quality of care and patient outcomes are improved; it has been demonstrated through several studies that the current state of nurses’ EBP competence and use is relatively suboptimal. For example, multiple studies conducted in the United States and other countries have demonstrated (a) nurses continue to use colleagues and personal experience to guide their clinical decision making (Estabrooks, Chong, Brigidear, & Profetto‐McGrath, ; Gerrish, Ashworth, Lacey, & Bailey, ; Pravikoff, Tanner, & Pierce, ; Thiel & Ghosh, ; Yadav & Fealy, ); (b) inconsistencies in whether nurses value research (Brown, Wickline, Ecoff, & Glaser, ; Cadmus et al., ; Fink, Thompson, & Bonnes, ; Melnyk et al., ; Munroe, Duffy, & Fisher, ); (c) nurses’ reasons for not implementing EBP may be due to individual or organizational barriers (Chummun & Tiran, ; Stetler, Ritchie, Rycroft‐Malone, Schultz, & Charns, ); and (d) within the pediatric nursing specialty, EBP competence and use is particularly problematic (Allmark & Spedding, ; Berg, ; Bourgeois et al., ; Buscariollo et al., ; Carroll & Gutmann, ; Cohen et al., ; Cohen, Uleryk, Jasuja, & Parkin, ; Gitterman & Hay, ; Hamm et al., ).…”