Chikungunya virus and dengue virus coinfection: a case report from Bangladesh

Rahim, Muhammad Abdur; Zaman, Shahana; Afroze, Samira Rahat; Haque, Hasna Fahmima; Afroz, Farhana; Samad, Tabassum; Uddin, Khwaja Nazim

doi:10.3329/imcjms.v12i1.35178

Cited by 3 publications

(3 citation statements)

References 7 publications

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“…3 Chikungunya-dengue co-infections are also to be remembered and such infections have been reported from Bangladesh. 10,[12][13][14][15] Clinical presentation of our cohort was not far different from two different reports from the same 2017 Dhaka outbreak published in literature. 9,16 Features were comparable with other chikungunya cohorts in literature as well.…”

Section: Discussionmentioning

confidence: 58%

“…Disorders (BIRDEM) General Hospital (14), Gulshan Maa O Shishu Clinic Ltd. (64) and LABAID Gulshan (29)] descriptive study was done including adult patients (>18 years) with confirmed diagnosis of chikungunya [confirmed by reverse transcriptase polymerase chain reaction (RT-PCR) (Qualitative One-Step Real-Time Reverse-Transcriptase PCR technology in the ABI 7500 DX instrument with SDS software) (12) or immunoglobulin M (IgM) against chikungunya (done by immunochromatographic test (ICT) for chikungunya IgM/ IgG by using commercially available kits manufactured by SD BIOSENSOR, Republic of Korea) (95)] from July 1, 2017 to October 31, 2017. Patients were followed-up clinically or over phone, as required; specially for rheumatological symptoms; whether they have entered in to sub-acute or chronic phase.…”

Section: A Multi-center [Bangladesh Institute Of Research and Rehabilmentioning

confidence: 99%

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Socio-demographic, Clinical and Laboratory Characteristics of a Chikungunya Cohort from the 2017 Dhaka Outbreak of Bangladesh

et al. 2019

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Background: Chikungunya is a rapidly spreading viral infection of global concern. Initial presentation of chikungunya infection is often indistinguishable from other viral infections. In Bangladesh, chikungunya is an emerging infection. In this report, we describe socio-demographic, clinical and laboratory characteristics of chikungunya in a selected group of Bangladeshi patients. Methods: A multi-center descriptive study was done including adult patients with chikungunya virus infection from July 1, 2017 to October 31, 2017. Diagnosis of chikungunya virus infection was confirmed by reverse transcriptase polymerase chain reaction (RT-PCR) or immunoglobulin M (IgM) against chikungunya. Results: Total patients were 107 including 61 (57%) males. Mean age of the study participants was 35.6 (range 19-84) years. Ninety three (86.9%) patients presented with fever and 14 (13.1%) patients (with history of recent fever) presented due to joint pain. Most (93, 86.9%) patients were managed as out-patient basis; while 14 (13.1%) patients required hospitalization. Common features were fever/history of fever, joint pain, rash and lymphadenopathy. Out of 93 patients who presented with fever, 79 (85%) had concomitant arthralgia/ arthritis, 70 (75.3%) had persistent joint symptoms beyond febrile illness requiring paracetamol, 63 (67.2%) patients had joint pain beyond 3 weeks (sub-acute phase) requiring paracetamol, non-steroidal antiinflammatory drugs or corticosteroids and 11 patients had passed 3 months since symptom onset (chronic phase) and only one (9%) had joint symptoms requiring hydroxychloroquine. There was no death. Conclusion: Clinical manifestation of chikungunya virus infection was comparable with other viral infections but arthritis/arthralgia was an important differentiating point. As chikungunya is an emerging infection in Bangladesh, physicians should have a high index of suspicion and care should be taken to exclude other viral infections specially dengue. Birdem Med J 2019; 9(2): 106-110

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Section: Discussionmentioning

confidence: 58%

Section: A Multi-center [Bangladesh Institute Of Research and Rehabilmentioning

confidence: 99%

Socio-demographic, Clinical and Laboratory Characteristics of a Chikungunya Cohort from the 2017 Dhaka Outbreak of Bangladesh

et al. 2019

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“…Common presentations included fever (93, 86.9%) or recent history of fever (14, 13.1%), joint pain (95, 88.8%), rash (25, 23.4%), pruritus (17, 15.9%), diarrhea and/or vomiting (30, 28%), lymphadenopathy (13, 12.1%), gum swelling and/or oral ulcer (5, 4.1%) and oedema (9, 8.4%). Two patients had chikungunya-dengue co-infections 7,8. Most (93, 86.9%) patients were managed as out-patient basis while 14 (13.1%) patients required hospitalization.…”

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confidence: 99%

Risk factors for acute kidney injury among patients with chikungunya: a multi-center experience from the 2017 chikungunya outbreak in Dhaka, Bangladesh

et al. 2019

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Background: Chikungunya is an emerging viral infection in Bangladesh. This self-limiting febrile illness may have acute life-threating features including cardiomyopathy and encephalitis. Acute kidney injury (AKI) is less well described complication of chikungunya. This study was designed to evaluate risk factors for AKI among patients with chikungunya virus infection. Methods: This case-control study was done in 3 different centers in Dhaka, Bangladesh from July to October 2017. Adult patients (>18 years) with confirmed diagnosis of chikungunya were included in this study. AKI was diagnosed as per Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline for Acute Kidney Injury. Patients suffering from chikungunya complicated by AKI were cases and those without AKI were controls. Results: Total patients were 107 (male 61) with a mean age of 35.6 (range 19-84) years. Common comorbidities were diabetes mellitus (DM) (20.6%), hypertension (17.8%) and chronic kidney disease (CKD) (12.1%). Common presentations included fever (86.9%) or recent history of fever (13.1%), joint pain (88.8%), rash (23.4%), pruritus (15.9%), gastro-intestinal (GI) features like diarrhea and/or vomiting (28%), lymphadenopathy (12.1%), gum swelling/oral ulcer (4.1%) and oedema (8.4%). Fourteen (13.1%) patients required hospitalization. Eleven (10.3%) cases were complicated by AKI. Among the risk factors for AKI, comorbidities like DM (OR 28.73, 95% CI 5.57-148.10, p 0.0001) and CKD (OR 31.0, 95% CI 2.94-326.7, p <0.0001), GI features (OR 16.07, 95% CI 3.22-80.14, p 0.0007), requirement of hospitalization (OR 23.10, 95% CI 2.37-226.31, p <0.0001) and use of angiotensin converting enzyme inhibitors/angiotensin receptor blockers (ACEIs/ARBs) (OR 6.65, 95% CI 1.77-24.98, p 0.005) were significant. Conclusions: One-tenth of adult patients suffering from chikungunya were complicated by AKI in this study. DM, CKD, diarrhea and/or vomiting, hospitalization and use of ACEIs/ARBs appeared as significant risk factors for AKI. Birdem Med J 2019; 9(3): 193-196

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SARS-CoV-2 and dengue virus coinfection in an adult with beta-thalassemia (trait): A case report from Bangladesh with literature review

Hossain¹,

Sarmin²,

Rahman³

et al. 2021

Heliyon

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Chikungunya virus and dengue virus coinfection: a case report from Bangladesh

Cited by 3 publications

References 7 publications

Socio-demographic, Clinical and Laboratory Characteristics of a Chikungunya Cohort from the 2017 Dhaka Outbreak of Bangladesh

Socio-demographic, Clinical and Laboratory Characteristics of a Chikungunya Cohort from the 2017 Dhaka Outbreak of Bangladesh

Risk factors for acute kidney injury among patients with chikungunya: a multi-center experience from the 2017 chikungunya outbreak in Dhaka, Bangladesh

SARS-CoV-2 and dengue virus coinfection in an adult with beta-thalassemia (trait): A case report from Bangladesh with literature review

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