Chickenpox, chickenpox vaccination, and shingles

Welsby, Philip D

doi:10.1136/pgmj.2005.038984

Cited by 15 publications

(13 citation statements)

References 19 publications

(9 reference statements)

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“…1 Other shorter term studies have also reported increases in HZ incidence. 42,43 The overall numbers of HZO cases with eye involvement combines both the overall increase in HZ cases and the increase in the rate of HZO with eye involvement within those HZ case (1.70 fold increase in HZ X 1.23 increase in HZO with eye involvement in HZ = 2.1 fold increase in numbers of HZO eye cases per year between 1980 and 2007).…”

Section: Discussionmentioning

confidence: 99%

Herpes Zoster Eye Complications: Rates and Trends

Yawn

Wollan

Sauver

et al. 2013

Mayo Clinic Proceedings

134

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Purpose To provide population based data on the risk, types and outcomes of eye involvement in herpes zoster (HZ). Methods A cohort study based on medical record review of patients diagnosed with HZ between January 1, 1980 and December 31, 2007. HZ was confirmed by typical rash and symptoms or laboratory testing and eye involvement was confirmed by ophthalmologists’ evaluation. Information was collected on all eye diagnoses, all HZ eye related visits, treatments, procedures and outcomes. Results Of the 2035 individuals with HZ in any dermatome, 184 patients (9.0%) had eye involvement. Mean age of the 184 was 62.6 with 5 cases in patients <21. Overall, 6.5% were immune suppressed at the time of the eye complications. The rate of increase of HZ eye involvement was 23% by decade from 1980 to 2007. Common eye complications were keratitis (76.2%), uveitis/iritis (46.6%) and conjunctivitis (35.4%). Recurrent keratitis and recurrent iritis/uveitis occurred in 6.9% and 7.4% respectively. Outcomes included six (3.3%) patients with new vision decrements to 20/200 or worse. Two individuals had successful corneal transplants. Another six (3.3%) individuals had lid ptosis that affected vision including one elderly woman with a permanent unilateral tarsorrhaphy. Severe HZ eye pain was reported to be directly responsible for one unsuccessful suicide attempt. No one developed ARN. A mean of 10.8 HZ eye visits per HZ patient with eye involvement were reported over a mean of 308 days. Conclusion Eye complications are common, result in significant health care utilization and in permanent vision decrement in about 6.6% of individuals with HZ eye involvement. Most health care utilization and long term adverse outcomes were in patients in whom administration of HZ prevention with the zoster vaccine would be possible.

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Section: Discussionmentioning

confidence: 99%

Herpes Zoster Eye Complications: Rates and Trends

Yawn

Wollan

Sauver

et al. 2013

Mayo Clinic Proceedings

134

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“…The universal vaccination is currently a widely debate subject, with objections[13,20,21] and defenders[22,23], including clinical and cost-effectiveness aspects [24-27]. …”

Section: Discussionmentioning

confidence: 99%

“…A vaccine against herpes zoster and post-herpetic neuralgia is currently being developed, and it is not well known about how this may influence the possible effect of varicella immunisation on herpes zoster and, as a result, on the indications and effectiveness of the herpes zoster vaccine[13,14]. …”

Section: Introductionmentioning

confidence: 99%

Varicella and Herpes Zoster in Madrid, based on the Sentinel General Practitioner Network: 1997–2004

Pérez-Farinós¹,

Ordobás²,

García-Fernández³

et al. 2007

BMC Infect Dis

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Background: Varicella (chickenpox) is the primary disease caused by varicella-zoster virus. It is extremely contagious and is frequent in children. Indeed, in the absence of vaccination, a high proportion of the population is liable to contract it. Herpes zoster -more frequent among adultsis caused by reactivation of the latent virus. The objective of this study is to describe the status of and time trend for varicella and herpes zoster in the Madrid Autonomous Region prior to the introduction of the vaccine to the general population.

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“…The incubation period is from 14 to 16 days (range [10][11][12][13][14][15][16][17][18][19][20][21]. This may be prolonged up to 28 days in immunocomprimised patients and in individuals who have received IVIG.…”

Section: Transmissionmentioning

confidence: 99%

“…and bacterial skin superinfection and septicaemia [2]. Reactivation of the latent virus causes herpes zoster [7,13].…”

Section: Morbidity and Mortalitymentioning

confidence: 99%

Varicella infection and the impact of late entry into the Irish healthcare system

Feeney

Muldoon

Barrett

et al. 2010

Journal of Infection and Public Health

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We present a case which highlights several areas of concern relating to the prevention and management of varicella in Ireland. We review the pathophysiology of this virus and highlight its greater potential for morbidity in certain groups, most particularly adult males. The experience and opinions with regard to varicella vaccination in the US and other temperate countries is reviewed along with evidence of changing epidemiology of varicella infection. The National Immunisation Advisory Committee (NIAC) guidelines are reviewed in the context of our experience.

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Chickenpox, chickenpox vaccination, and shingles

Cited by 15 publications

References 19 publications

Herpes Zoster Eye Complications: Rates and Trends

Herpes Zoster Eye Complications: Rates and Trends

Varicella and Herpes Zoster in Madrid, based on the Sentinel General Practitioner Network: 1997–2004

Varicella infection and the impact of late entry into the Irish healthcare system

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