2010
DOI: 10.1080/00015458.2010.11680596
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Chewing Gum Reduces Postoperative Ileus after Open Appendectomy

Abstract: Chewing gum ameliorates recovery after open appendectomy by reducing postoperative ileus. It is a cheap and helpful treatment to be recommended in developing countries in Africa.

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Cited by 29 publications
(29 citation statements)
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“…Overall, all studies had low risk of bias. Only one trial was at high risk of bias for sequence generation (not truly random), which was randomized based on hospital record number . But the method of randomization was unclear (not reported) in five trials .…”
Section: Resultsmentioning
confidence: 99%
“…Overall, all studies had low risk of bias. Only one trial was at high risk of bias for sequence generation (not truly random), which was randomized based on hospital record number . But the method of randomization was unclear (not reported) in five trials .…”
Section: Resultsmentioning
confidence: 99%
“…In Ngowe’s study in 2010 on 46 patients with open appendectomy, the mean time of gas passage was 2.2 and 3.0 days in the gum-chewing and the control group (21). In Choi’s study on 60 patients in 2011, the mean time to the passage of flatus was 60 h and 48 h in gum-chewing and the control group which the difference was statistically significant (22); whilst, Quah reported no remarkable difference between the two groups in terms of gas passage. There is not yet an independent investigation on the exact gum chewing mechanism of action, however, some theories discuss chewing as a form of sham feeding that stimulates food digestion and secretion of salivary and hepatic glands through the vagus nerve stimulation and increases the plasma concentration of gastrin, neurotensin, pancreatic polypeptide, and duodenal alkaline secretion.…”
Section: Discussionmentioning
confidence: 95%
“…This reduction was not always clinically significant; a few hours' difference in bowel movement often did not result in a reduction of LOS. Most of these studies involved small patient numbers and had very specific inclusion criteria, such as ‘left‐sided colon or rectal cancer surgery’ only.…”
Section: Discussionmentioning
confidence: 99%