We describe the case of a 75-year-old man affected by a chronic obstructive pulmonary disease and chronic renal failure admitted to our emergency department for dyspnea and interscapular stabbing pain. Chest radiography showed diffuse parenchymal consolidation in the lower right lung with bronchiectasis, but the treatment for infection disease did not improve the clinical conditions of the patient. According to Wells score indicating an intermediate risk for pulmonary embolism, we performed a chest ultrasonography that showed ultrasonographic patterns of thromboembolism. Because the presence of chronic renal failure limited the execution of a helical computed tomographic pulmonary angiography, a pulmonary scintigraphy was performed confirming the diagnosis of pulmonary embolism. Our case suggested that chest ultrasonography can be a valuable tool for early detection of pulmonary embolism and to establish immediately an appropriate therapy.Pulmonary embolism is a common and potentially lethal cardiopulmonary disease with nonspecific signs and symptoms [1] so that its diagnosis could be difficult and requires a high index of clinical suspicion by the emergency physician and is, therefore, frequently underdiagnosed and undertreated [2]. Chest radiography is the first imaging diagnostic modality used in the emergency department (ED), although it may often show nonspecific and indirect signs or it may even be normal.Pulmonary angiography is currently the criterion standard [3], but it is rarely used because of its invasive nature and the relative high risk of complications [4].Helical computed tomographic pulmonary angiography (HCTPA) has been recently established as the reference modality, with high sensitivity and specificity [3], but it has limitations in detecting injury in subsegmental arteries [5].On the other hand, ventilation/perfusion lung scan is often not sufficiently conclusive [6][7][8], although it is sometimes used [9,10].However, critically ill patients may sometimes not tolerate any of these diagnostic modalities, or adequate equipment might not be available in the ED.In these cases, chest ultrasonography that exhibited high sensitivity [3] can play a useful role in directing the physician to formulate the correct diagnosis and to optimize the treatment, improving the prognosis.A 75-year-old man was admitted to our ED for dyspnea and interscapular stabbing pain, exacerbated by deep inspiration and cough, started 3 weeks ago.The patient was a former smoker and had a history of right pleurisy and spontaneous pneumothorax and was affected by a chronic obstructive pulmonary disease and a chronic renal failure syndrome. In the last 3 months, the patient was treated twice for a pulmonary infection by Pseudomonas aeruginosa.Vital signs at admission were heart rate of 75 beats per minute, blood pressure of 165/80 mm Hg, respiratory rate of 22 breaths per minute, oxygen saturation of 96% during oxygen administration (2 L/min) by nasal probes, Glasgow Coma Scale of 15, and no fever.The patient was tach...