Chest Radiography in Coronavirus Disease 2019 (COVID-19): Correlation with Clinical Course

Zhou, Joel Cheng'en; Hui, Terrence Chi Hong; Tan, Cher Heng; Khoo, Hau Wei; Young, Barnaby Edward; Lye, David C.; Lee, Yeong Shyan; Kaw, Gregory

doi:10.47102/annals-acadmedsg.2020106

Cited by 7 publications

(3 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Another case series from Singapore published by Zhou et al confirmed that around 40% of patients with COVID-19 PCR positive had initial normal CXR; however, these patients were stable and most of them did not require admission to hospital. One of their patients had initial normal CXR, but as the patient deteriorated and required 35% of oxygen, the repeat CXR started to show features of classic COVID-19 in the form of unilateral consolidation that later on progressed later to bilateral consolidation [ 13 ].…”

Section: Discussionmentioning

confidence: 99%

COVID-19 and Adenovirus Multi-Lobar Pneumonia on CT Scan in a Patient with Repeatedly Normal Chest X-Rays Despite Severe Hypoxia and the Need for Non-Invasive Ventilation

Sreh

Jameel

Musleh

et al. 2021

Cureus

View full text Add to dashboard Cite

The British Society of Thoracic Imaging (BSTI) has published clear guidance on the classification of chest X-ray (CXR) findings in coronavirus disease 2019 (COVID-19) patients, which are summarised in four main categories: COVID-classical, COVID-indeterminate, COVID-normal, or non-COVID. We report the case of a 34-year-old lady who is otherwise fit and well. She presented with typical COVID-19 symptoms requiring supplemental oxygen, with normal CXR and COVID-19 reverse transcriptase-polymerase chain reaction (RT-PCR) swab on admission. Her condition deteriorated after 24 hours with severe hypoxia requiring up to 60% oxygen. Repeat CXR was normal, which was followed by computed tomography pulmonary angiogram (CTPA) that ruled out pulmonary embolism; however, CTPA confirmed multi-lobar pneumonia consistent with COVID-19. The patient was admitted to the intensive care unit for non-invasive ventilation (NIV) and ongoing care. Extended respiratory screening confirmed positive COVID-19 antibodies and positive adenovirus swabs. The patient also developed COVID-19 related hepatocellular injury and myocarditis in the absence of other causes. These were treated by a multidisciplinary team, and the patient achieved full recovery after three weeks. This case highlights the fact that normal CXR does not rule out COVID-19 pneumonia even in the severely hypoxic patient requiring NIV. Also, it is important to investigate for other potential causes of hypoxia in a deteriorating patient, such as pulmonary embolism and non-COVID causes of pneumonia.

show abstract

Section: Discussionmentioning

confidence: 99%

COVID-19 and Adenovirus Multi-Lobar Pneumonia on CT Scan in a Patient with Repeatedly Normal Chest X-Rays Despite Severe Hypoxia and the Need for Non-Invasive Ventilation

Sreh

Jameel

Musleh

et al. 2021

Cureus

View full text Add to dashboard Cite

show abstract

“…The most common type of articles in this category were case reports and those about the symptoms, signs, and complications of COVID-19 . These articles described the various ways in which COVID-19 could present, such as olfactory loss [206,209,214,219], radiological findings [217,221,231,232], and various other presentations. Viral transmission of COVID-19 was the next most commonly studied [93,[243][244][245][246][247][248][249][250][251][252][253][254][255], which looked at the various modes of transmission [245,247,249,[252][253][254], and contamination of the environment and PPE [243,244,248].…”

Section: Covid-19 Pathology (94 Articles)mentioning

confidence: 99%

One Year on: An Overview of Singapore’s Response to COVID-19—What We Did, How We Fared, How We Can Move Forward

Anand

Shuy

Lee³

et al. 2021

IJERPH

View full text Add to dashboard Cite

Background—One year has passed since the first COVID-19 case in Singapore. This scoping review commemorates Singaporean researchers that have expanded the knowledge on this novel virus. We aim to provide an overview of healthcare-related articles published in peer-reviewed journals, authored by the Singapore research community about COVID-19 during the first year of the pandemic. Methods—This was reported using the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) protocol. It included healthcare-related articles about COVID-19 published between 23 January 2020 and 22 January 2021 with a Singapore-affiliated author. MEDLINE, Embase, Scopus, Web of Science, CINAHL, PsycINFO, Google Scholar, and local journals were searched. The articles were screened independently by two reviewers. Results—The review included 504 articles. Most of the articles narrated the changes to hospital practice (210), while articles on COVID-19 pathology (94) formed most of the non-narrative papers. Publications on public health (61) and the indirect impacts to clinical outcomes (45) were other major themes explored by the research community. The remaining articles detailed the psychological impact of the pandemic (35), adaptations of medical education (30), and narratives of events (14). Conclusion—Amidst a resurgence of community cases involving variant COVID-19 strains, the resources from the research community will provide valuable guidance to navigate these uncertain times.

show abstract

“…The author searched PubMed for literature reports on COVID-19 from January 20 th , 2020 to the present day. There are many reports at least 300 articles on the non-contrast enhanced high-resolution computed tomography (HRCT) features of the lungs during the onset of COVID-19; however, few studies have described the radiological changes and outcome of residual lesions in the lungs of recovered patients 3,4 .Here, we review the HRCT features of 118 recovered COVID-19 patients at 22−465 days post-discharge. These features can be utilized to predict the prognosis and guide rehabilitation treatment of COVID-19.…”

Section: Introductionmentioning

confidence: 99%

Natural History of Radiological Changes on CT Chest from COVID-19 Infection Rehabilitation Patients

Peng¹

2021

Preprint

View full text Add to dashboard Cite

Object： To investigate the chest CT manifestations of convalescent patients with COVID-19 in recovery phase. Methods: 118 convalescent patients diagnosed as COVID-19 were followed up. According to their medical history, they were divided into 47 cases of severe disease group and 71 cases of mild disease group. Multi-slice spiral CT, high-resolution CT and pulmonary function were examined. Results: 67 rehabilitated cases are normal on CT scan. The other CT findings were: (1) ground glass opacity lesions, including: localized patchy ground glass density lesions; Multi lobes and multi-stage ground glass opacities; Diffuse ground glass opacities lesions in both lungs. (2) The interlobular interstitium and interlobular septum were thickened. (3) Subpleural arc shadow/Subpleural lines. (4) Irregular fiber cord shadow/Irregular lines. (5) Tractive bronchiectasis. (6) Nodular consolidation of air space. (7) Cavitary lesions. No obvious mediastinal lymph node enlargement and pleural effusion were found. Pulmonary imaging and pulmonary function were improved after repeated reexamination. There was significant difference in CT findings and pulmonary function indexes between severe group and mild group (P < 0.05). Conclusion: The pulmonary manifestations of some convalescent patients with COVID-19 are basically normal. Ground glass density lesions are the main CT manifestations of convalescent patients, accompanied by varying degrees of pulmonary interstitial hyperplasia. The severe group had more severe pulmonary manifestations and poor pulmonary function than the mild group. With the extension of time, pulmonary lesions and pulmonary function gradually improved.

show abstract

Chest Radiography in Coronavirus Disease 2019 (COVID-19): Correlation with Clinical Course

Cited by 7 publications

References 15 publications

COVID-19 and Adenovirus Multi-Lobar Pneumonia on CT Scan in a Patient with Repeatedly Normal Chest X-Rays Despite Severe Hypoxia and the Need for Non-Invasive Ventilation

COVID-19 and Adenovirus Multi-Lobar Pneumonia on CT Scan in a Patient with Repeatedly Normal Chest X-Rays Despite Severe Hypoxia and the Need for Non-Invasive Ventilation

One Year on: An Overview of Singapore’s Response to COVID-19—What We Did, How We Fared, How We Can Move Forward

Natural History of Radiological Changes on CT Chest from COVID-19 Infection Rehabilitation Patients

Contact Info

Product

Resources

About