Chest pain in young people: Is cannabis a risk factor?

Myocardial ischaemia associated with tetrahydrocannabinol intake in a teenage boy: A case report

“…THC, which is an active substance in cannabis, affects cardiovascular system by stimulating the activity of sympathetic nervous system, causing tachycardia, an increase in blood pressure and decreased left ventricular EF. In addition, decreased end diastolic volume and stroke volume were observed in THC users 2,3 …”

“…These changes can lead to coronary vasoconstriction and, in turn, to temporary myocardial ischaemia and angina pectoris symptoms, as well as ischaemic changes in ECG in patients with correct coronary arteries. 2,3,5 These people usually have not had a history of similar ailments in the past. According to the work by Desai et al, the risk of myocardial infarction (MI) increases by 8% in patients who smoke marijuana recreationally.…”

“…Marijuana‐induced increase in carboxyhaemoglobin level in blood and subsequent reduction of normal haemoglobin saturation lead to an increased demand for blood supply in the myocardium as a consequence of reduced oxygen supplementation. These changes can lead to coronary vasoconstriction and, in turn, to temporary myocardial ischaemia and angina pectoris symptoms, as well as ischaemic changes in ECG in patients with correct coronary arteries 2,3,5 . These people usually have not had a history of similar ailments in the past.…”

“…Patients affected by this drug are often young, with no other risk factors, which suggests marijuana use as a possible trigger of these symptoms 1 . In scientific research and literature, it is gradually emphasised that cannabis use by young healthy people can lead to ischaemic myocardial incidents 2 . Due to the ever‐increasing popularity of this drug in both the USA and Western European countries, numerous cases of post‐marijuana cardiac incidents have been reported 3 .…”

“…is gradually emphasised that cannabis use by young healthy people can lead to ischaemic myocardial incidents. 2 Due to the everincreasing popularity of this drug in both the USA and Western European countries, numerous cases of post-marijuana cardiac incidents have been reported. 3 THC, which is an active substance in cannabis, affects cardiovascular system by stimulating the activity of sympathetic nervous system, causing tachycardia, an increase in blood pressure and decreased left ventricular EF.…”