Chest Pain in Cancer Patients

Bima, Paolo; Lopez-Ayala, Pedro; Koechlin, Luca; Boeddinghaus, Jasper; Nestelberger, Thomas; Okamura, Bernhard; Muench-Gerber, Tamar S.; Sanzone, Alessandra; Skolozubova, Daria; Djurdjevic, David; Rubini Gimenez, Maria; Wildi, Karin; Miro, Oscar; Martínez-Nadal, Gemma; Martin-Sanchez, Francisco J.; Christ, Michael; Keller, Dagmar; Lindahl, Bertil; Giannitsis, Evangelos; Mueller, Christian

doi:10.1016/j.jaccao.2023.08.001

Cited by 6 publications

(3 citation statements)

References 50 publications

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“…This may suggest that cardiac effects of cancer and cardiotoxic cancer therapies are associated with a more pronounced cTnT than cTnI release. 13 Both cTnT and cTnI are strongly associated with cardiac disease and with similar prognostic value for all-cause mortality in the general population. However, whereas cTnI is more predictive of cardiovascular mortality, cTnT has been more strongly associated with noncardiovascular mortality, suggesting a potential increased specificity for cardiac injury for cTnI over cTnT.…”

Section: Discussionmentioning

confidence: 98%

Impact of the ESC Cardio-Oncology Guidelines Biomarker Criteria on Incidence of Cancer Therapy–Related Cardiac Dysfunction

Mecinaj,

Gulati,

Ree

et al. 2024

JACC: CardioOncology

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Section: Discussionmentioning

confidence: 98%

Impact of the ESC Cardio-Oncology Guidelines Biomarker Criteria on Incidence of Cancer Therapy–Related Cardiac Dysfunction

Mecinaj,

Gulati,

Ree

et al. 2024

JACC: CardioOncology

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“…Association of neoplastic disease and acute coronary syndromes are causes of death in both high and low in come countries [4][5][6]. In the research by Paolo Bima and colab 2023, we can note that: patients with neoplatisc pathology have a very high risck of myocardial infarction, when they come in emergency departement with acute chest pain [6,7]. Daniela Barroso and colab., report a rare case of spontaneous pneumomediastin witch began with acute chest pain associated with other symptoms [8].…”

Section: Discussionmentioning

confidence: 99%

Acute chest pain... Where?

Gabriela-Florentina,

Florica

2023

Open J Clin Med Case Rep

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Acute chest pain is a common symptom in emergency medicine. Approaching acute chest pain in emergency departments is a challenge epidemiologically, clinically and organizationally [1]. This symptom requires increased attention from medical professionals, this requiring a primary and careful evaluation for patient, imagining and paraclinical investigations. Attention should also be paid to cardiovascular risk factors (age, high blood pressure, smoking, pre-existing cardiovascular disease, obesity) [2]. In emergency medicine, primary assessment consists of ABCDE evaluation (1. Airway, 2. Breathing, 3. Circulation, 4. Disability, 5. Exposure) [3].

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“…As a result, an acute illness, such as a small myocardial infarction that has minor repercussions on overall health, may reveal a more severe diagnosis. Dyspnea and low oxygen saturation are evaluated extensively in the emergency room to the detriment of other symptoms that are often neglected [22,23].…”

Section: Discussionmentioning

confidence: 99%

What to Do When There Is Something Unexpected?

Ivan,

Lighezan,

Ardelean

et al. 2024

Life

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Background: Myocardial infarction is currently the leading cause of death worldwide, followed by malignant neoplasms. The presence of both within the same patient obviously increases the risk of death, as many coronary events are detected in patients diagnosed with cancer. Diagnosis of an occult digestive cancer in the acute phase of myocardial infarction is most frequently prompted by a hemorrhagic complication. Case summary: This case features an 81-year-old male patient diagnosed with acute myocardial infarction, treated with primary percutaneous intervention (PCI), who developed post-stenting hemorrhagic complications in the first 24 h due to the presence of two different concomitant malignant neoplasms. The outcome was favorable in the acute phase, even if de-escalation therapy was given immediately post-stenting, and intrastent residual thrombotic risk was high. Conclusions: The presence of bleeding complications in patients with acute myocardial infarction should mobilize resources in search of a neoplastic cause, especially a digestive one. However, other locations should be looked for, depending on the source of bleeding.

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Chest Pain in Cancer Patients

Cited by 6 publications

References 50 publications

Impact of the ESC Cardio-Oncology Guidelines Biomarker Criteria on Incidence of Cancer Therapy–Related Cardiac Dysfunction

Impact of the ESC Cardio-Oncology Guidelines Biomarker Criteria on Incidence of Cancer Therapy–Related Cardiac Dysfunction

Acute chest pain... Where?

What to Do When There Is Something Unexpected?

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