Chemotherapy supply chain management, safe-handling and disposal in Ethiopia: the case of Tikur Anbessa specialized hospital

Fentie, Atalay Mulu; Mekonen, Zelalem Tilahun; Gizachew, Zelalem; Hailemariam, Mahlet; Clark, Scott G.; Richardson, Jaime; Muluneh, Benyam

doi:10.1080/08880018.2022.2139028

Cited by 2 publications

(1 citation statement)

References 14 publications

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“…47 Unfortunately, access to chemotherapy drugs in the country is limited and unaffordable, some drugs are not available at all pharmacies, 48 and drug stock-outs are common. 49 To sustain the viability of HSCT service continuous medication supply and effective utilization are fundamental.…”

Section: Financing Hsctmentioning

confidence: 99%

Why and How Should Ethiopia Establish a Stem Cell Transplant Service? A Review Article

Mekonnen¹,

Farris²

2023

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Ethiopia is attempting to reduce cancer-related morbidity and mortality through a strategic national cancer control plan but according to Globocan 2020, hematologic malignancies particularly leukemia and non-Hodgkin's lymphoma rank among the top five leading causes of new cancer incidence and cause of death among all age groups in both sexes. Hematopoietic stem-cell transplantation (HSCT) is an advanced treatment modality that makes the only effective treatment for cancer and non-cancer-related hematologic diseases unresponsive to conventional therapy. Patients who need stem cell transplants must travel to abroad countries to get the treatment. Meanwhile, the Ethiopian National Specialty and Subspecialty Roadmap sets the goal of establishing HSCT centers in 2020-2029 GC, yet leaders and planners must start taking steps to put the setup in place. Setting up an HSCT facility is challenging for developing countries due to the high costs, limited infrastructure, and need for intensive medical staff training; however, several nations have been able to start successful stem cell transplant programs. This review summarizes the basic steps and requirements of the program in light of guidelines recommendations and lessons learned from other developing countries. It also highlights possible cost-effective opportunities, bottlenecks, and areas that will require work and investment to make the objective reality in Ethiopia.Provides key information to assist administrators and policymakers to set priorities in planning and making informed decisions to establish and maintain the service.

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Section: Financing Hsctmentioning

confidence: 99%

Why and How Should Ethiopia Establish a Stem Cell Transplant Service? A Review Article

Mekonnen¹,

Farris²

2023

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Chemotherapy safe handling practices in Ethiopia: A comprehensive multi-center evaluation

Webb,

Matys,

Collins

et al. 2024

J Oncol Pharm Pract

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Introduction The increasing incidence of cancer and capacity for cancer care in Ethiopia has led to an upsurge in chemotherapy use in the country; however, studies indicate that there is a gap in the safe handling of chemotherapy by healthcare workers. There exists a need to understand if such unsafe practices occur in Ethiopia and, if so, which areas along the chemotherapy life cycle need the most improvement. Methods This study utilized a multi-method design through an online survey administered to health care professionals and evaluative site visits of eight cancer units in Addis Ababa, Ethiopia to understand the current conditions of chemotherapy handling. In addition, a survey was conducted among Ethiopian health care professionals from across the country. Results Fifty-five percent of survey participants disagreed or strongly disagreed that there are systems in place to identify, prevent, and address chemotherapy hazards in their workplace, and 71% of respondents denied having an active and effective health and safety committee and/or worker health and safety representative where they work. At evaluative site visits, only 30% of health care workers met the minimum guidelines for proper hand hygiene, and 20% of health care workers used adequate Personal Protective Equipment according to guidelines across the chemotherapy lifecycle. Conclusions Results of this study indicate an urgent need for implementation of evidence-based interventions to improve chemotherapy handling in Ethiopia so that all patients and health care workers are protected from the hazardous toxicities of these drugs.

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Chemotherapy supply chain management, safe-handling and disposal in Ethiopia: the case of Tikur Anbessa specialized hospital

Cited by 2 publications

References 14 publications

Why and How Should Ethiopia Establish a Stem Cell Transplant Service? A Review Article

Why and How Should Ethiopia Establish a Stem Cell Transplant Service? A Review Article

Chemotherapy safe handling practices in Ethiopia: A comprehensive multi-center evaluation

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