Chemotherapy of malignant hemangiopericytoma of childhood.Report of a case and review of the literature

Ortega, Jorge A.; Finklestein, Jerry Z.; Isaacs, Hart; Hittle, Robert E.; Hastings, Newlin

doi:10.1002/1097-0142(197103)27:3<730::aid-cncr2820270332>3.0.co;2-9

Cited by 55 publications

(13 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…12 Regimens including doxorubicin, interferon-a, and a variety of other agents have been used for recurrence, widespread metastases, unresectable disease, and palliation, but little survival benefit is apparent and the systemic toxicities of these drugs are significant. 12,32,33,35,36 Local recurrence is expected in up to 40% of cases. 12,37 Metastasis is common and is frequently delayed more than 3 years from treatment of the primary lesion.…”

Section: Discussionmentioning

confidence: 99%

Concurrent Cochlear Implantation with Resection of Skull Base Hemangiopericytoma Following Sudden Deafness in an Only-Hearing Ear

Ransom¹,

Judy²,

Bigelow³

2009

Skull Base

View full text Add to dashboard Cite

A 72-year-old man with a known left acoustic neuroma, left-sided deafness, and a recently diagnosed right infratemporal fossa (ITF) hemangiopericytoma, presented with sudden deafness in his right ear. Imaging revealed right-sided skull base extension and a large intracranial tumor component. The patient underwent a frontotemporal crainiotomy with concomitant ITF approach. Complete tumor resection was possible, though invasion of the otic capsule was present. Immediately postresection, a cochlear implant (CI) was performed via a transmastoid approach. Full electrode insertion was achieved and confirmed by visualization through the dehiscent middle fossa floor. Mastoid obliteration was then performed with a free fat graft. Postoperative imaging confirmed complete tumor resection (Simpson grade I) and adequate CI placement. Follow-up magnetic resonance imaging was performed at 6 and 12 months, and no tumor recurrence was seen. Prior to CI activation, the patient was completely deaf bilaterally. At 18-month follow-up, however, excellent hearing was achieved with the right CI (16 of 22 electrodes active), and the patient is now conversational with no obvious deficit. His cognitive function is excellent, corresponding to preoperative status, and he is independent in his activities of daily living. Following adjuvant radiation, our patient remains disease free at 18 months.

show abstract

Section: Discussionmentioning

confidence: 99%

Concurrent Cochlear Implantation with Resection of Skull Base Hemangiopericytoma Following Sudden Deafness in an Only-Hearing Ear

Ransom¹,

Judy²,

Bigelow³

2009

Skull Base

View full text Add to dashboard Cite

show abstract

“…Very few cases of infantile/congenital hemangiopericytoma of the tongue have been reported in the literature [3,17,19]. Though an innocent looking tumor, it has a high recurrence rate, Kauffman and Stout [12] found it to be 28% and Brockbank 52.5% [4].…”

Section: Discussionmentioning

confidence: 99%

Extensive tongue hemangiopericytoma in a child: modified combined modality of treatment to preserve well functioning tongue

Alabdulhadi

Burezq

Nguyễn

et al. 2004

International Journal of Pediatric Otorhinolaryngology

View full text Add to dashboard Cite

“…This can be attributed to the rarity of this tumor and the insufficient number of patients for randomized trials. Nevertheless, previous reports have documented a significant favorable response rate to chemotherapy of soft tissue sarcomas, including HPC [5,[12][13][14][15]. The role of radiotherapy in achieving local control after incomplete surgical removal seems to be established in the majority of reports [10].…”

Section: Discussionmentioning

confidence: 99%

HEMANGIOPERICYTOMA IN AN ADOLESCENT GIRL: A Case Report

Athanassiadou¹,

Kourti²,

Papageorgiou³

et al. 2004

Pediatric Hematology and Oncology

View full text Add to dashboard Cite

Hemangiopericytoma (HPC) is a rare soft tissue tumor The few published reports account for the little information available on its clinical management. Here the authors report the successful treatment of an adolescent girl with rare HPC of the tongue. After incomplete surgical excision of the tumor she was admitted to the Hematology-Oncology Department and was treated with a 3-drug combination regimen (ifosfamide, actinomycin D, vincristine) for 8 weeks. She achieved partial remission in week 9 based on the magnetic resonance imaging (MRI)findings. Conventional radiation therapy was initiated at week 9 and continued until week 16. At week 20, according to the MRI findings, she achieved complete remission and continuation therapy was initiated. The young girl has been alive without evidence of the disease for the last 3 years of follow-up. In conclusion, the current report indicates that in cases of incomplete surgical excision of the tumor, chemotherapy and radiotherapy seem to be effective.

show abstract

Chemotherapy of malignant hemangiopericytoma of childhood.Report of a case and review of the literature

Cited by 55 publications

References 10 publications

Concurrent Cochlear Implantation with Resection of Skull Base Hemangiopericytoma Following Sudden Deafness in an Only-Hearing Ear

Concurrent Cochlear Implantation with Resection of Skull Base Hemangiopericytoma Following Sudden Deafness in an Only-Hearing Ear

Extensive tongue hemangiopericytoma in a child: modified combined modality of treatment to preserve well functioning tongue

HEMANGIOPERICYTOMA IN AN ADOLESCENT GIRL: A Case Report

Contact Info

Product

Resources

About