Chemotherapy-induced acute kidney injury: epidemiology, pathophysiology, and therapeutic approaches
Rafaella Maria da Cunha Lyrio,
Bruna Reis Araújo Rocha,
Ana Luiza Rodrigues Mascarenhas Corrêa
et al.
Abstract:Despite significant advancements in oncology, conventional chemotherapy remains the primary treatment for diverse malignancies. Acute kidney injury (AKI) stands out as one of the most prevalent and severe adverse effects associated with these cytotoxic agents. While platinum compounds are well-known for their nephrotoxic potential, other drugs including antimetabolites, alkylating agents, and antitumor antibiotics are also associated. The onset of AKI poses substantial risks, including heightened morbidity and… Show more
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