Chemotherapy and Chemoprophylaxis of Malaria

Chaudhuri, R. N.; Chakravarty, Nirmal; Chaudhuri, M. N. Rai; Poti, Shannon

doi:10.1136/bmj.1.4758.568

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1953

2019

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“…It was thought at first that the clearance time obtained in this type of trial with chloroquine is longer by about half a day when compared with figures quoted by investigators whose reports were based on clinical trials in East Africa (Handfield-Jones, 1949), in Tunisia (Durand, Schneider, and Dupoux, 1949), in Indo-China (Canet, 1950). Our average figures for the chloroquine clearance time of asexual parasitaemia due to P. falciparum are, however, almost identical with 1.84 days reported from India by Chaudhuri, Chakravarty, Rai Chaudhuri, and Poti (1952), and very close to 2 days observed by Singh and Kalyanum (1952).…”

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confidence: 90%