Chemosurgery

Mohs, F. E.; Desprez, John D.

doi:10.1097/00006534-197909000-00030

Cited by 17 publications

(21 citation statements)

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“…Although no guiding philosophy exists regarding the use interval and contact time with Mohs paste, the progress and depth of consolidation depend on contact time. Reported contact times range from a few minutes to 48 hours [10]. Hemostatic effects have been seen with times ranging from a few minutes to 10 minutes [7].…”

Section: Discussionmentioning

confidence: 99%

“…The fixative used in a Mohs procedure contains zinc chloride and is referred to as Mohs paste. In this technique, fixation and excision are repeated until no residual tumor can be found in the specimen by microscopic examination [10]. In recent years, the use of Mohs chemosurgery has become widespread for the primary purpose of improving QOL.…”

Section: Introductionmentioning

confidence: 99%

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Locally advanced breast cancer made amenable to radical surgery after a combination of systemic therapy and Mohs paste: two case reports

et al. 2012

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IntroductionChemotherapy and other systemic therapies are the primary treatments for patients with unresectable, locally advanced breast cancer. The clinical application of supportive care using Mohs paste has become widespread for the purpose of improving patients’ quality of life. Here, we report two cases of locally advanced breast cancer, for which the patients underwent radical surgery after a combination of systemic therapy and Mohs chemosurgery.Case presentationsPatient 1 was a 90-year-old Japanese woman with right breast cancer diagnosed as stage IIIB (T4bN1M0). The treatment included Mohs paste application and hormonal therapies. Patient 2 was a 60-year-old Japanese woman with right breast cancer diagnosed as stage IIIB (T4cN2aM0). Her treatment included Mohs paste application, together with chemotherapy (four cycles of 5-fluorouracil, epirubicin, and cyclophosphamide, and four cycles of docetaxel). In both cases, a reduction in the primary tumor volume was observed, and radical mastectomy and axillary lymph node dissection were possible without relaxation incision or skin flap.ConclusionWe report patients with no distant metastases who were able to undergo radical resection after a combination of systemic therapy and Mohs chemosurgery. For locally advanced breast cancer, Mohs chemosurgery, in addition to multidisciplinary treatment, is useful.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Locally advanced breast cancer made amenable to radical surgery after a combination of systemic therapy and Mohs paste: two case reports

et al. 2012

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“…Chemosurgery, also referred to as Mohs' surgery, 28 microscopically controlled excision, 29,30 histographic surgery, 20 or microcontrolled surgery, 32 is the standard against which other methods of skin‐cancer eradication must be compared 44 . The fresh‐tissue technique is a modification of the originally described Mohs' chemosurgical fixed‐tissue method.…”

Section: Discussionmentioning

confidence: 99%

“…The fresh‐tissue variant of Mohs' surgery clearly demonstrates advantages over the fixed‐tissue technique 28–31 . However, critics have pointed out that certain cases still require using the fixed‐tissue method 8,22,27,32–34 . One criticism of fresh‐tissue chemo‐surgery is the difficulty encountered in pinpointing the location of residual tumor in extensive lesions.…”

Section: Historical Backgroundmentioning

confidence: 99%

Mohs' Surgery, Fresh‐Tissue Technique: Our Technique with a Review

Cottel

Proper

1982

The Journal of Dermatologic Surgery and Oncology

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“…Poorer prognosis as poor host response increases likelihood of recurrence and metastasis (Day and Rowe, 1993;Mohs and Snow, 1985;Mohs, 1980;Leibovitch et al, 2005a) …”

Section: Histologymentioning

confidence: 99%

Textbook of Plastic and Reconstructive Surgery

Butler¹,

Ghali²,

Kalaskar³

2016

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A CIP catalogue record for this book is available from The British Library.This book is published under a Creative Commons Attribution Non-commercial Non-derivative 4.0 International license (CC BY-NC-ND 4.0). This license allows you to share, copy, distribute and transmit the work for personal and non-commercial use providing author and publisher attribution is clearly stated. Further details about CC BY licenses are available at http://creativecommons.org/ licenses/by/4.0The publishers cannot guarantee the accuracy of any information about dosage and application contained in this book. The user is advised to always check the product information and clinical procedures with the most up-to-date published product information and the most recent codes of conduct and safety regulations. The authors and the publishers do not accept responsibility or legal liability for any errors in the text or misuse or misapplication of material in this work.ISBN: 978-1-910634-37-0 (Hbk.) ISBN: 978-1-910634-38-7 (Pbk.) ISBN: 978-1-910634-39-4 (PDF) ISBN: 978-1-910634-40-0 (epub) ISBN: 978-1-910634-41-7 (mobi)

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Chemosurgery

Cited by 17 publications

References 0 publications

Locally advanced breast cancer made amenable to radical surgery after a combination of systemic therapy and Mohs paste: two case reports

Locally advanced breast cancer made amenable to radical surgery after a combination of systemic therapy and Mohs paste: two case reports

Mohs' Surgery, Fresh‐Tissue Technique: Our Technique with a Review

Textbook of Plastic and Reconstructive Surgery

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