Chemoradiotherapy-Induced Esophagitis Pain Relieved by Topical Morphine: Three Cases

Gairard-Dory, A.; Schaller, Carine; Mennecier, B.; Molard, Anita; Gourieux, B.; Beretz, L.; Quoix, Élisabeth

doi:10.1016/j.jpainsymman.2005.05.008

Cited by 7 publications

(2 citation statements)

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“…Topical morphine has been applied alone as a solution [23] or mixed with other topical vehicles/medications (e.g., intrasite gel [24] and silver sulfadiazine cream [25]). Studies have shown that painful therapy-induced mucositis/stomatitis in cancer patients could be alleviated using topical morphine mouthwashes [26][27][28][29]. The onset of the analgesic effect of topical morphine is often immediate or within a few hours.…”

Section: Topical Application Of Morphine/opioidsmentioning

confidence: 99%

Current concepts of pain management for cancer patients

2008

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Pain management is one of the most important issues confronted when treating patients with malignant diseases. Since its release/publication in 1986, the World Health Organization's three-step analgesic ladder has helped to greatly improve pain management in cancer patients. However, many questions about this three-step analgesic ladder have been raised and its application in the clinical setting remains a controversial subject. This review article explores the frontline treatment of cancer pain with morphine and the different routes of fentanyl administration used in cancer pain management. The combination of multiple opiates/opioids has been shown to result in more effective cancer pain management; however, the exact benefits of such opiate/opioid combinations have yet to be established. This article also discusses recent advances in the topical application of morphine and in the combination of ketamine and morphine. It explores the updated treatment principles of neuropathic pain in advanced-stage cancer patients, which incorporate the use of anti-depressants, anti-convulsants, and opioids. Finally, this article reviews the available data and clarifies the general principles for using opioids in cancer patients with renal insufficiency. We hope that this information will be helpful in improving pain management in cancer patients and in facilitating further research.

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Section: Topical Application Of Morphine/opioidsmentioning

confidence: 99%

Current concepts of pain management for cancer patients

2008

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“…In literature, the major causative agents of esophageal injuries have been identified to be tetracycline, doxycycline, and clindamycin; however, frequently used drugs such as other anti-inflammatory agents, alendronate, iron sulfate, dabigatran, and vitamin C were reported to cause similar damage (6,8,9,12,15). Telithromycin was reported to cause chemotherapy-induced esophagitis in rare cases (16,17). In this study, the causative agent was detected to be tetracycline in two cases, doxycycline in two cases, and tramadol HCl in one case.…”

Section: Discussionmentioning

confidence: 54%

Drug-induced esophagitis: Incidence, clinical and endoscopic findings, and management

Uyanıkoğlu

2019

Endoskopi Gastrointestinal

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This study aimed to investigate the incidence, clinical and endoscopic findings, and management of esophagitis in patients referred to the Endoscopy Unit of Erzurum Education and Research Hospital in a 1-year progressive follow-up period. MATERIALS and METHODS Patients referred to the Endoscopy Unit of Erzurum Regional Education and Research Hospital underwent esophagogastroduodenoscopy (EGD) between February 2010 and February 2011, forwarded from emergency and normal outpatient units, other outpatient units and wards, and other hospitals in Erzurum and peripheral hospitals. Endoscopic evaluations were performed for all reasons, most frequently for dyspepsia

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Integrative Therapies to Support Palliative and End-of-Life Care in Lung Disease

Gordon-Kolb

2011

Integrative Therapies in Lung Health and Sleep

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Chemoradiotherapy-Induced Esophagitis Pain Relieved by Topical Morphine: Three Cases

Cited by 7 publications

References 7 publications

Current concepts of pain management for cancer patients

Current concepts of pain management for cancer patients

Drug-induced esophagitis: Incidence, clinical and endoscopic findings, and management

Integrative Therapies to Support Palliative and End-of-Life Care in Lung Disease

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