Chemometrics Evaluation of Phytochemicals and Antioxidant Activities of the Extracts of<i>Chaerophyllum bulbosum</i>Roots and Aerial Parts

Tel‐Çayan, Gülsen; Deveci, Ebru; Çayan, Fatih; Molo, Zeynep; Duru, Mehmet Emin; Yeşıl, Yeter

doi:10.1080/00032719.2021.1930026

Cited by 10 publications

(5 citation statements)

References 36 publications

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“…Furthermore, the contribution of the original variables to the principal components can be used to identify some potential associations between metabolites, and each PC also reflected their importance in the principal components [36] , [37] . The loading plot's values for the variables on the x- and y-axes represent their contribution to the model fit, the farther away from the origin, the more that component contributes to the sample variance [38] .…”

Section: Resultsmentioning

confidence: 99%

Identification of volatile compounds and metabolic pathway during ultrasound-assisted kombucha fermentation by HS-SPME-GC/MS combined with metabolomic analysis

Wang

Ahmad

Zhu

et al. 2023

Ultrasonics Sonochemistry

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Section: Resultsmentioning

confidence: 99%

Identification of volatile compounds and metabolic pathway during ultrasound-assisted kombucha fermentation by HS-SPME-GC/MS combined with metabolomic analysis

Wang

Ahmad

Zhu

et al. 2023

Ultrasonics Sonochemistry

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“…The phenolic compounds and organic acids were characterized in terms of UV data and retention times compared with commercial standards. The calibration curve was drawn via the injection of standard compounds at a concentration range of 0.0∼1.0 ppm to identify and quantify the phenolic compounds [69] . The results were described as μg per g of dry weight (dw).…”

Section: Methodsmentioning

confidence: 99%

“…The calibration curve was drawn via the injection of standard compounds at a concentration range of 0.0 ~1.0 ppm to identify and quantify the phenolic compounds. [69] The results were described as μg per g of dry weight (dw).…”

Section: Analysis Of Phenolic Compositionmentioning

confidence: 99%

HPLC‐DAD Analysis and Versatile Bioactivities of Turkish Sunflower Honeys Using Chemometric Approaches

Duru

Eroğlu

Tel‐Çayan

et al. 2023

Chemistry & Biodiversity

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Sunflower honey (SH) is bright yellow, fragrant, pollen‐flavoured, slightly herbaceous and has a unique taste. The present research aims to examine the enzyme inhibitory, antioxidant, anti‐inflammatory, antimicrobial and anti‐quorum sensing activities and phenolic compositions of 30 sunflower honeys (SHs) produced from several regions of Turkey with chemometric study. SAH from Samsun exhibited the best antioxidant activity in β‐carotene linoleic acid (IC50: 7.33±0.17 mg/mL) and CUPRAC (A0.50: 4.94±0.13 mg/mL) assays, anti‐urease activity (60.63±0.87 %) and anti‐inflammatory activity against COX‐1 (73.94±1.08 %) and COX‐2 (44.96±0.85 %). SHs exhibited mild antimicrobial activity against the test microorganisms while they showed high quorum sensing inhibition zones measured in the range of 42–52 mm against the CV026 strain. The phenolic composition was determined by high performance liquid chromatography with diode array detection (HPLC‐DAD) system and levulinic, gallic, p‐hydroxybenzoic, vanillic and p‐coumaric acids were identified in all studied SHs. The classification of SHs was performed the using PCA and HCA. This study revealed that phenolic compounds and biological properties are effective in classification of SHs according to their geographical origin. The results suggest that studied SHs could be valued as potential agents with versatile bioactivities in oxidative stress‐related disease, microbial infections, inflammation, melanoma, and peptic ulcer.

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“…Phenolics and organic acids were compared with reference compounds and identified according to UV data and retention times. The calibration graphic was plotted by injection of reference compounds, i. e., levunilic acid, gallic acid, trans‐ aconitic acid, protocatechuic acid, luteolin, catechin, p‐ hydroxy phenyl acetic acid, (4‐hydroxyphenyl)‐ethanol, p‐ hydroxy benzoic acid, kaempferol, 6,7‐dihydroxy coumarin, chlorogenic acid, vanillic acid, 3‐hydroxy benzoic acid, vanillin, p‐ coumaric acid, guaiacol, ferulic acid, coumarin, rutin, 2‐hydroxy cinnamic acid, myricetin, rosmarinic acid, quercetin, trans‐ cinnamic acid, chrysin in the concentration range 0.0 and 1.0 μg/mL for the qualitative and quantitative identification [71] . Results are specified as μg per gram of dry weight (dw).…”

Section: Methodsmentioning

confidence: 99%

Citrus Honeys from Three Different Regions of Turkey: HPLC‐DAD Profiling and in Vitro Enzyme Inhibition, Antioxidant, Anti‐Inflammatory and Antimicrobial Properties with Chemometric Study

Tel‐Çayan,

Çiftçi,

Taş‐Küçükaydın

et al. 2023

Chemistry & Biodiversity

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The objectives of the present study are to compare the phenolic profiles and biological activities of 15 citrus honey samples from three different locations in Turkey using a chemometric approach. The HPLC‐DAD analysis was used to determine phenolic profiles. Nineteen phenolic compounds were identified. Gallic acid (107.14‐717.04 μg/g) was recorded as the predominant compound. AF (Antalya‐Finike) had the highest antioxidant activity in ABTS•+ (IC50: 18.01±0.69 mg/mL), metal chelating (IC50: 6.20±0.19 mg/mL) and CUPRAC (A0.50: 12.05±0.68 mg/mL) assays, while it revealed the best anti‐inflammatory activity against COX‐2 (17.28±0.22%) and COX‐1 (43.28±0.91%). AM (Antalya‐Manavgat) was the most active in β‐carotene‐linoleic acid (IC50: 10.05±0.19 mg/mL), anti‐urease (38.90±0.69%), anti‐quorum sensing and antimicrobial activities. AKO1 (Adana‐Kozan‐1) in DPPH• (IC50: 34.25±0.81 mg/mL) assay, AKU1 (Antalya‐Kumluca‐1) in tyrosinase inhibition activity (37.73±0.38%) assay, AKU2 (Antalya‐Kumluca‐2) in AChE (10.55±0.63%) and BChE (9.18±0.45%) inhibition activity assays showed the best activity. Chemometric tools were applied to the phenolic compositions and biological properties. PCA and HCA ensured that 15 citrus honey samples were grouped into 3 clusters. The results showed that myricetin, kaempferol, vanillin, protocatechuic acid, rosmarinic acid, rutin, vanillic acid, gallic acid, catechin and p‐hydroxyphenyl acetic acid are phenolic compounds that can be used in the classification of citrus honeys.

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Chemometrics Evaluation of Phytochemicals and Antioxidant Activities of the Extracts ofChaerophyllum bulbosumRoots and Aerial Parts

Cited by 10 publications

References 36 publications

Identification of volatile compounds and metabolic pathway during ultrasound-assisted kombucha fermentation by HS-SPME-GC/MS combined with metabolomic analysis

Identification of volatile compounds and metabolic pathway during ultrasound-assisted kombucha fermentation by HS-SPME-GC/MS combined with metabolomic analysis

HPLC‐DAD Analysis and Versatile Bioactivities of Turkish Sunflower Honeys Using Chemometric Approaches

Citrus Honeys from Three Different Regions of Turkey: HPLC‐DAD Profiling and in Vitro Enzyme Inhibition, Antioxidant, Anti‐Inflammatory and Antimicrobial Properties with Chemometric Study

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