Chemoenzymatic total synthesis of rotigotine <i>via</i> IRED-catalyzed reductive amination

Tang, Dongyu; Ma, Yaqing; Bao, Jinping; Gao, Shushan; Man, Shuli; Cui, Chengsen

doi:10.1039/d4ob00072b

Org. Biomol. Chem.

2024

DOI: 10.1039/d4ob00072b

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Chemoenzymatic total synthesis of rotigotine via IRED-catalyzed reductive amination

Dongyu Tang,

Yaqing Ma,

Jinping Bao

et al.

Abstract: An engineered imine reductase (IRED) was developed specifically for 2-tetralone substrate, and utilized in the total synthesis of rotigotine.

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Chemoenzymatic total synthesis of rotigotine via IRED-catalyzed reductive amination

Abstract: An engineered imine reductase (IRED) was developed specifically for 2-tetralone substrate, and utilized in the total synthesis of rotigotine.

Cited by 1 publication

References 40 publications

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