Chemistry of spices: bornyl 4-methoxybenzoate from Ferula ovina (Boiss.) Boiss. (Apiaceae) induces hyperalgesia in mice

Abstract

Essential oil constituents impart this spice with both antinociceptive and hyperalgesic potentially flavor-related properties.

Chemical Composition of the Essential Oil and Diethyl Ether Extract of Trinia glauca (L.) Dumort. (Apiaceae) and the Chemotaxonomic Significance of 5‐O‐Methylvisamminol

“…Schischk , Peucedanum praeruptorum Dunn , and Prionosciadium thapsoides ( DC .) Mathias . The distribution of 5 and related natural products appears to be restricted to the Apiaceae plant family.…”

“…5‐ O ‐Methylvisamminol, (furo)chromone identified in the extract of T. glauca , has a limited occurrence in plants. Furthermore, its distribution seems to be limited to Apiaceae taxa . Thus, 5‐ O ‐methylvisamminol and related compounds could be useful in (chemical) phylogeny and might serve as taxonomic markers for Apiaceae (family and/or subfamily level).…”

“…Fresh above‐ground parts (250 g) of T. glauca were subjected to hydrodistillation with ca . 2.5 l of distilled H 2 O for 2.5 h using an original Clevenger ‐type apparatus . The obtained oil was separated by extraction with Et 2 O and dried over anhydrous MgSO 4 .…”

Essential‐oil inspired synthetic libraries: synthesis, spectral and gas‐chromatographic properties of new fenchyl esters

“…Essential oils (EOs) and their constituents, important flavouring and fragrance agents used in foodstuff, are often biologically/pharmacologically active (some are even toxic or are known allergens); their chemical fingerprints are frequently used in chemotaxonomy . Thus, knowing the exact chemical composition of EOs is important for both safety (eg commercially used oils) and scholarly reasons (eg metabolomic and chemotaxonomic studies).…”

“…However, EOs represent complex mixtures of secondary metabolites. They may sometimes contain up to several hundreds of different, but structurally and biosynthetically related compounds (these most often originate from terpene and/or phenylpropanoid metabolic pathways and frequently have similar chemical/physical properties), present in highly varying relative amounts (from traces up to several tens of percents) . This, in combination with often a small available sample size (on the laboratory scale, available EO amount can be less than one gram), renders the analysis of EOs a challenging task.…”