Chemistry behind in neem (Azadirachta indica) as medicinal value to living forms-A review

Shrirangasami, SR; Murugaragavan, R; Rakesh, SS; Ramesh, P.

doi:10.22271/phyto.2020.v9.i6g.12936

J Pharmacogn Phytochem

2020

DOI: 10.22271/phyto.2020.v9.i6g.12936

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Chemistry behind in neem (Azadirachta indica) as medicinal value to living forms-A review

SR Shrirangasami¹,

R Murugaragavan²,

SS Rakesh³

et al.

Abstract: The Azhadirachtin in Indian society has been considered higher than kalpavriksha, the mythological and ethanobotanical beneficial properties. The efficacy of neem as a medicine has been documented in several different ancient treatments like the Atharvana Veda, the Ghrhyasutra and Sutragrantha and in puranas. The acidic principles in neem as margosic acid with three acetive constituents, viz., nimbin, nimbidin and nimbinene. Chemically related and biogenetically derivable from a tetracyclicterpene are the key … Show more

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Cited by 10 publications

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“…Taxonomical classification of Azadirachta indica as azadirachtin, azadiradione, nimbin, salanin, salannol, and vepininetc49 . The trunk bark contains nimbinin, nimbidin, nimbosterol, essential oils, and tannins50 .…”

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A Review on Antidiabetic Edible Plants Used by Garo Community of Meghalaya, India

Debnath,

Singh,

Saha

et al. 2024

JNR

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Metabolic syndrome characterized by inadequate insulin secretion. The world's 2.8% of the population is affected by diabetes, and it is projected to reach 4.4% by 2030. Recently plant-based products have given significant results for curing diabetics. In this review article, we have summarized the taxonomical classification, phytochemical investigation, toxicological study, and anti-diabetic activity of nine edible plants traditionally used by Garo communities of Meghalaya to cure diabetic mellitus. The book “Antidiabetic Plants in India and Herbal Based Antidiabetic Research” by K Chandrasekhar Naidu and T Pullaiah helps to choose the anti-diabetic plant species of Meghalaya and Scopus, Web of Science, PubMed, Google Scholar databases have been used for collecting the complete information of plants. Literature reveals that all the selected plants contain bio-active constituents (alkaloids, phenols, flavonoids, tannins, terpenoids, glycosides, etc.), do not give a toxic effect at the highest level of dose, and give significant anti-diabetic activity. This review article helps natural researchers discover of new anti-diabetic drug.

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confidence: 99%

A Review on Antidiabetic Edible Plants Used by Garo Community of Meghalaya, India

Debnath,

Singh,

Saha

et al. 2024

JNR

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Proximate composition, some phytochemical constituents, potential uses, and safety of neem leaf flour: A review

Andersa,

Tamiru,

Teka

et al. 2024

Food Science & Nutrition

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Globally, there is a growing concern about avoiding using artificial compounds in food ingredients, food preservation, and packaging. Among the parts of the neem tree, leaf flour is one of the most commonly used parts in some countries for food and medicinal purposes and is known for containing several nutrients and phytochemicals. In this review, the proximate composition, phytochemical constituents, potential uses, and safety issues of neem leaf flour are discussed. Neem leaf flour contains high levels of crude protein, total carbohydrate, crude fat, and fiber and moderate amounts of crude fat and ash. In addition, it contains numerous health‐promoting phytochemical constituents. Some phytochemicals, such as ascorbic acid, saponin, total alkaloids, carotenoids, total phenols, total flavonoids, and the total antioxidant capacity of neem leaf flour, have been critically discussed. Neem leaf flour has various potential applications in food science, such as preserving foods and preparing food packaging materials. However, researchers' perspectives on its safety are not yet in agreement. In general, the proximate compositions, phytochemical constituents, potential uses, and safety issues of neem leaf flour were compiled and critically reviewed. In addition, research is needed to identify all the toxic substances found in neem leaves and develop methods to eliminate them that hinder their use for various purposes in food. Further research is needed to develop food products from neem leaf flour and evaluate its nutritional value and phytochemical constituents.

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Production and characterization of neem leaves biochar: Effect of two different retort carbonization systems

Adeniyi,

Iwuozor,

Adeleke

et al. 2023

Bioresource Technology Reports

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Chemistry behind in neem (Azadirachta indica) as medicinal value to living forms-A review

Cited by 10 publications

References 12 publications

A Review on Antidiabetic Edible Plants Used by Garo Community of Meghalaya, India

A Review on Antidiabetic Edible Plants Used by Garo Community of Meghalaya, India

Proximate composition, some phytochemical constituents, potential uses, and safety of neem leaf flour: A review

Production and characterization of neem leaves biochar: Effect of two different retort carbonization systems

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