Chemistry and pharmacology of Bidens pilosa: an overview

Abstract

Bidens pilosa L. is an edible herb and has been traditionally used for a wide range of ailments in many countries. The aim of this review is to present comprehensive information of the chemical constituents, nutraceutical and ethnomedical uses as well as the biological and pharmacological effects and toxicity of this plant based on 218 literary sources reported over 40 years. Major chemical constituents (including 301 compounds) belonging to polyacetylenes, polyacetylene glycosides, flavonoids, flavone glycosides, aurones, chalcones, okanin glycosides, phenolic acids, terpenes, pheophytins, fatty acids and phytosterols have been identified or isolated from the different parts of this plant. Many of them have been considered as the bioactive compounds which are potentially responsible for the pharmacological actions. Various types of preparations, extracts and individual compounds derived from this plant have been found to possess biological and pharmacological activities such as anti-malarial, anti-allergy, antihypertensive and smooth muscle relaxant, anti-cancerogenic, anti-diabetic, anti-inflammatory, anti-microbial, antioxidant. The results of data analysis on the chemicals, pharmacological and toxicological characteristics of B. pilosa validate the view of its folk worldwide-medicinal uses. This herb has a great beneficial therapeutic property and is possibly used for complement or alternative to pharmaceutical drugs in some specific cases. However, this herb is known as hyperaccumulator and as-excluder; therefore, harvesting the herb for medicinal uses should be judiciously cautioned.

Morphological and Biochemical Study of Bidens pilosa on the Effects of Extract of Urochloa ruziziensis

“…The Bidens pilosa L. weed is an annual plant originating in South America, but is widely distributed in most regions of the world (Holm et al, 1991;Xuan & Khanh, 2016). The seeds of this plant are widely dispersed by wind and animals, so a single plant can produce approximately 5000 seeds that can remain viable for years when buried in the soil (Xuan & Khanh, 2016).…”

“…The Bidens pilosa L. weed is an annual plant originating in South America, but is widely distributed in most regions of the world (Holm et al, 1991;Xuan & Khanh, 2016). The seeds of this plant are widely dispersed by wind and animals, so a single plant can produce approximately 5000 seeds that can remain viable for years when buried in the soil (Xuan & Khanh, 2016). Due to its rapid growth, this plant is found in most parts of the world and may be in both cultivated and uncultivated fields causing problems in food crops in many countries (Holm et al, 1991;Khanh et al, 2009;Mitich, 1994;Xuan & Khanh, 2016).…”

Revealing the organic dye and mordant composition of Paracas textiles by a combined analytical approach

“…Several avonoids were unequivocally identi ed in samples PAR-001, PAR-003 and PAR-005 (the EIC chromatograms of yellow sample PAR-001 are presented in Figure 6b): luteolin 7-O-glucoside (m/z = 447.070), okanin glucoside (m/z = 449.105), coreopsin (m/z = 433.113), okanin (m/z = 287.030), luteolin (m/z = 285.030) and butein (m/z = 271.057) [43,44]. Okanin and butein and their glucosides occur in several species, such as Bidens, native to South America [45], but in this case, the positive matching with the pro le of the extracts of the petals of Cosmos sulphureus, performed in the same conditions, allowed us to suggest that the latter is the raw source used for dyeing [46]. The use of Cosmos sulphureus for dyeing in yellow-orange hues is reported in the literature [26,27] but, to the best of our knowledge, this is the rst time that it has been identi ed in ancient textiles.…”

“…A small peak for aluminium was observed in the accumulated spectra of the maps collected from textile fragments [3]; however, the data maps showed no speci c distribution of the relative levels of aluminium between the variously coloured threads. Nevertheless, it appears likely that aluminium mordants were used in the Paracas textiles, given that Peru has natural resources of alum salts [45].…”

Potencial alelopático de Stryphnodendron adstringens (Mart) Coville na germinação e crescimento inicial de picão-preto

“…Dentre as plantas de difícil controle, destaca-se o picão-preto (Bidens pilosa L. -Asteraceae) que é uma planta herbácea originária da América do Sul, mas que atualmente encontra-se distribuída em áreas tropicais e subtropicais em todo o mundo (Xuan & Khanh 2016). No Brasil, está presente em quase todo território, porém, concentra-se nas áreas agrícolas das regiões Sul e Centro-Oeste, na qual constitui em uma das mais importantes plantas daninhas de culturas anuais e perenes, sendo apontada como tal em mais de 40 países.…”