Abstract:Drug‐resistant bacteria are a worldwide public health concern. As the prevalence of multi‐drug resistant pathogens outpaces the discovery of new antibacterials, it is of importance to explore the structure‐activity relationships for series of known bactericides with proven scaffolds. Herein, we assembled a set of 507 fluoroquinolone analogues all experimentally tested for their inhibition potency against four pathogens: Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoni… Show more
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