ChemInform Abstract: β‐THIOCYANATOVINYLCARBONYL COMPOUNDS, 1. PREPARATION AND SEPARATION OF THE Z E ISOMERS OF β‐THIOCYANATOVINYL ALDEHYDES

Muehlstaedt, M.; Braemer, R.; Schulze, B.

doi:10.1002/chin.197621166

Cited by 2 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…1). The synthesis of 1a, b, d was performed by a known method from corresponding ketones [9], while 2-thiocyanatobenzaldehyde was prepared via a two-step procedure from 2-aminobenzaldehyde [10].…”

Section: Resultsmentioning

confidence: 99%

Synthesis of N,N’-Linked Isothiazolium Salts via Intramolecular Cyclocondensation of Hydrazonium Salts

Zakharova

Siegemund-Eilfelda

Sieler

et al. 2006

Zeitschrift Für Naturforschung B

View full text Add to dashboard Cite

Interaction of β -thiocyanatovinyl aldehydes with N-amino heterocycles leads to formation of α, β -unsaturated hydrazonium salts dependent on the functional surroundings. The latter can undergo further intramolecular cyclocondensation giving rise to N, N -linked isothiazolium salts as the final product. The isolated hydrazonium salts, not undergoing ring formation, have s-trans conformation of the azadiene system.

show abstract

Section: Resultsmentioning

confidence: 99%

Synthesis of N,N’-Linked Isothiazolium Salts via Intramolecular Cyclocondensation of Hydrazonium Salts

Zakharova

Siegemund-Eilfelda

Sieler

et al. 2006

Zeitschrift Für Naturforschung B

View full text Add to dashboard Cite

show abstract

“…The two b-thiocyanatovinyl aldehydes 6 [R 1 = R 2 = Me; R 1 R 2 = -(CH 2 ) 4 -] used in this study were synthesized by a known method from the corresponding ketones. 15 Conversions were carried out with N-aminophthalimide (7), N-amino-4(3H)-quinazolinones 8, and heterocycles of type 9 ( Figure 2).…”

mentioning

confidence: 99%

Synthesis of N,N′-Linked Bisazaheterocycles with Sulfonamide Structure via Oxidation of S,N-Heteroaromatic Cations

Zakharova¹,

Tanarro²,

Gütschow³

et al. 2008

Synthesis

View full text Add to dashboard Cite

N-Phthalimidyl-and N-quinazolinyl-substituted 3-hydroperoxy-, 3-hydroxy-and 3-oxoisothiazole 1,1-dioxides have been synthesized by the sequence of oxidation reactions from N,N¢-linked isothiazolium perchlorates with hydrogen peroxide, MMPP, and pyridinium dichromate. Isothiazolium salts without acceptor substituents did not give N-substituted sultams. Novel N,N¢-bisazaheterocycles were investigated as inhibitors of acetylcholinesterase (AChE) and human leukocyte elastase (HLE). Two 2,3-dihydro-3-hydroperoxy-2-(phthalimid-1-yl)isothiazole 1,1-dioxides were found to inhibit AChE.

show abstract

ChemInform Abstract: β‐THIOCYANATOVINYLCARBONYL COMPOUNDS, 1. PREPARATION AND SEPARATION OF THE Z E ISOMERS OF β‐THIOCYANATOVINYL ALDEHYDES

Abstract: Aus den β‐Chlor‐vinylaldehyden (I) bzw. (III) werden durch Reaktion mit NH4‐ bzw. K‐thiocyanat die β‐Thiocyanatovinylaldehyde (II) bzw. (IV), die bis auf (IId) als Z/E‐Isomerengemische vorliegen, dargestellt.

Cited by 2 publications

References 0 publications

Synthesis of N,N’-Linked Isothiazolium Salts via Intramolecular Cyclocondensation of Hydrazonium Salts

Synthesis of N,N’-Linked Isothiazolium Salts via Intramolecular Cyclocondensation of Hydrazonium Salts

Synthesis of N,N′-Linked Bisazaheterocycles with Sulfonamide Structure via Oxidation of S,N-Heteroaromatic Cations

Contact Info

Product

Resources

About