ChemInform Abstract: Versatile Synthesis of 4‐Spiro‐β‐lactam‐3‐carbonitriles via the Intramolecular Nucleophilic Cyclization of N‐(p‐Hydroxyphenyl)cyanoacetamides.
Abstract:cyanoacetamides. -A range of N-substituted spiro-cyclohexadienoyl--lactam-3-carbonitriles is prepared by condensation of N-alkylated anilines with cyanoacetic acid followed by oxidative cyclization. -(ABDELLAOUI, H.; XU*, J.; Tetrahedron 70 (2014) 29, 4323-4330, http://dx.
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