ChemInform Abstract: Thermally Induced Denitrogenative Annulation for the Synthesis of Dihydroquinolinimines and Chroman‐4‐imines.

Abstract

Thermally Induced Denitrogenative Annulation for the Synthesis of Dihydroquinolinimines and Chroman-4-imines. -Various aniline and phenol derivatives bearing an N-tosyl-1,2,3-triazole side chain are investigated with a view to preparing the title heterocycles under metal-free conditions at an elevated temperature. An electron-donating group is required at the meta position of the aryl moieties; no reaction is observed if ortho or para substituents are present. The tosylimine function in the products can be further elaborated as is demonstrated for derivative (IVb). -(CHOU, C.-H.; CHEN, Y.-Y.; RAJAGOPAL, B.; TU, H.-C.; CHEN, K.-L.; WANG, S.-F.; LIANG, C.-F.; TYAN, Y.-C.; LIN*, P.-C.; Chem. -Asian J. 11 (2016) 5, 757-765, http://dx.