Abstract:The Synthesis of 3-Bromo-2,4,5-trifluorobenzoic Acid and Its Conversion to 8-Bromoquinolonecarboxylic Acids. -A series of the title substances (IX) are synthesized via the key intermediate (II). The synthesis of (IX) is a significant improvement of the literature procedure currently available for the synthesis of these compounds which have equal as or higher activity than ciprofloxacin and sparfloxacin against mycobacteria. -(RENAU, T. E.; SANCHEZ, J. P.; DOMAGALA, J. M.; J.
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