ChemInform Abstract: The Michael Addition of 1,2‐Cyclohexanedione to β‐Nitrostyrenes. Part 1. Synthesis of 3‐Aryl‐5,6‐dihydrobenzofuran‐7(4H)‐ones.

Abstract

The Michael Addition of 1,2-Cyclohexanedione to β-Nitrostyrenes. Part 1. Synthesis of 3-Aryl-5,6-dihydrobenzofuran-7(4H)-ones. -The simple protocol proceeds via initial Michael addition, intramolecular cyclization, elimination of the nitrite ion and air oxidation. The process is found to be strongly dependent on the base stoichiometry. -(SIMPKINS, C. M.; HUNT*, D. A.; Tetrahedron Lett. 54 (2013) 26, 3371-3373, http://dx.