ChemInform Abstract: Tandem Pd‐Catalyzed C—C Coupling/Recyclization of 2‐(2‐Bromoaryl)cyclopropane‐1,1‐dicarboxylates with Primary Nitro Alkanes.

Abstract

Tandem Pd-Catalyzed C-C Coupling/Recyclization of 2-(2-Bromoaryl)cyclopropane-1,1-dicarboxylates with Primary Nitro Alkanes. -The title process provides the first successful synthetic approach to 1H-2,3-benzoxazine 3-oxides. The optically active substrate ((R)-IV) reacts without significant racemization. -(MIKHAYLOV*, A. A.; DILMAN, A. D.; NOVIKOV, R. A.; KHOROSHUTINA, Y. A.; STRUCHKOVA, M. I.; ARKHIPOV, D. E.; NELYUBINA, Y. V.; TABOLIN, A. A.; IOFFE, S. L.; Tetrahedron Lett. 57 (2016) 1, 11-14, http://dx.