ChemInform Abstract: Synthesis of (.+‐.)‐trans‐2,5‐Dialkylpyrrolidines from the Lukes‐Sorm Dilactam: Efficient Preparation of (.+‐.)‐trans‐2‐Butyl‐5‐heptylpyrrolidine and Analogs Present in Ant Venoms.

Abstract

Starting from the Lukes‐Sorm dilactam (I) the preparation of (±)‐trans‐2‐butyl‐5‐heptylpyrrolidine (VIa) is accomplished in seven steps and in an overall yield of 6%.