ChemInform Abstract: Synthesis of Substituted Cyclohexenyl‐, Cyclohexadienylarylamines.

Abstract

2001 amines amines (benzene compounds) Q 0120 16 -105 Synthesis of Substituted Cyclohexenyl-, Cyclohexadienylarylamines. -The preparation of title compounds (III) and (IV) is achieved by acid-catalyzed amination of cyclohexanones (I). -(SOROKIN, V. V.; GRIGOR'EV, A V.; RAMAZANOV, A. K.; KRIVEN'KO, A. P.; Russ.

Synthesis and Structure of Diisopropyl 6-Hydroxy-6-methyl-4-oxocyclohexane-1,3-dicarboxylates and Their Reactions with Nucleophilic Reagents

“…Reactions of cyclic hydroxy ketones containing methoxy-or ethoxycarbonyl groups in positions 1 and 3 of the cyclohexane ring are known to react with hydrazine hydrate at the 1,3-dioxo fragment; the subsequent heterocyclization gives the corresponding tetrahydroindazoles [5,6]. Under similar conditions, bis(tert-butoxycarbonyl)-substituted analogs are converted into 6-hydrazones [5].…”

“…With the goal of elucidating the effect of alkyl radical in the alkoxycarbonyl group on the reactivity of 1,3-bis(alkoxycarbonyl)-substituted cyclohexanones (cyclic β-hydroxy ketones) [1][2][3][4][5][6] we synthesized 2-substituted diisopropyl 6-hydroxy-6-methyl-4-oxocyclohexane-1,3-dicarboxylates and studied their structure and reactions with mono-and difunctional nitrogen-containing nucleophiles. Compounds Ia-If were obtained by the known method, namely by diketone condensation of isopropyl acetoacetate with aromatic and heterocyclic aldehydes under conditions of base catalysis [1] (in the presence of piperidine; Scheme 1).…”

Synthesis and structure of (thio)semicarbazonocyclohexanedicarboxylates. Crystalline and molecular structure of diethyl 4-hydroxy-4-methyl-2-phenyl-6-thiosemicarbazonocyclohexane-1,3-dicarboxylate

“…Their reactions with nitrogen-centered nucleophiles have been well documented; depending on the nucleophile structure, these reactions lead to the formation of enamines, oximes, fused heterocycles, and heterocyclic spiro compounds whose structure was determined by spectral methods and X-ray analysis [4][5][6][7].…”