ChemInform Abstract: Synthesis of Spiro‐Fused (C5)‐Isoxazolino‐(C4)‐pyrazolones (1‐Oxa‐2,7,8‐triazaspiro[4,4]‐2,8‐dien‐6‐ones) via 1,3‐Dipolar Cycloaddition and Cycloelimination.

Abstract

Synthesis of Spiro-Fused (C5)-Isoxazolino-(C4)-pyrazolones (1- 7,4]-2,8-dien-6-ones) via 1,3-Dipolar Cycloaddition and Cycloelimination.-An efficient and selective route to title compounds is reported. They are of biological interest. -(SAMMELSON, ROBERT E.; GURUSINGHE, CHAMINDRA D.; KURTH, JEFFREY M.; OLMSTEAD, MARILYN M.; KURTH, MARK J.; J. Org. Chem. 67 (2002) 3, 876-882; Dep. Chem., Univ. Calif., Davis, CA 95616, USA; EN)