ChemInform Abstract: Synthesis of Silicon‐Functionalized Dimethylsilyl Enol Ethers from Ketones.

Abstract

Synthesis of Silicon-Functionalized Dimethylsilyl Enol Ethers fromKetones.-The symmetrical dimethylsilyl bisenol ethers (III) are obtained by reaction of the ketones (I) with dichloromethylsilane (II) in the presence of triethylamine and sodium iodide. Reaction of ketones with N,N-diethylaminodimethylchlorosilane (V) in the presence of triethylamine and sodium iodide followed by various conversions provides a useful synthesis of silicon-functionalized dimethylsilyl enol ethers, e.g. (VI), (VIII), and the unsymmetrical dimethylsilyl bis-enol ethers (IX). -(RATHKE, M. W.; WEIPERT, P. D.; Synth. Commun. 21 (1991) 12-13, 1337-1351 Dep. Chem., Michigan State Univ., East Lansing, MI 48824, USA; EN)