ChemInform Abstract: Synthesis of Pyrrolizin‐3‐ones by Flash Vacuum Pyrolysis of Pyrrol‐2‐ ylmethylidene Meldrum′s Acid Derivatives and 3‐(Pyrrol‐2‐yl)propenoic Esters.

Abstract

Synthesis of Pyrrolizin-3-ones by Flash Vacuum Pyrolysis of Pyrrol-2-ylmethylidene Meldrum's Acid Derivatives and 3-(Pyrrol-2yl)propenoic Esters.-A more extensive study of the scope of the title reaction leading to heterocycles such as (II) and (IV) is presented. The synthesis of the starting material is described and mechanistical aspects are discussed in detail. -(CAMPBELL, S. E.; COMER, M. C.; DERBYSHIRE, P. A.; DESPINOY, X. L. M.; MCNAB, H.; MORRISON, R.; SOMMERVILLE, C. C.; THORNLEY, C.; J.