ChemInform Abstract: Synthesis of Optically Active 2‐Arylpropionic Acids.

Abstract

2001 carboxylic acids carboxylic acids (naphthalene compounds) Q 0940 -123Synthesis of Optically Active 2-Arylpropionic Acids.-(S)-Naproxen (IV) is prepared starting from ketone (I) and (S)-sorbitol (II) via ZnCl 2 -catalyzed formation of optically active acetals and their stereospecific rearrangement forming the ester (III) and subsequent hydrolysis. -(WANG, B.; MA, H.-ZH.; Synth.