ChemInform Abstract: Synthesis of Optically Active 2‐Fluoroalk‐1‐en‐3‐yl Esters and Chirality Transfer in Their Claisen‐Type Rearrangements.

Abstract

2008Halogenated carboxylic acids and esters P 0260 Synthesis of Optically Active 2-Fluoroalk-1-en-3-yl Esters and Chirality Transfer in Their Claisen-Type Rearrangements. -Chiral esters (V) and (VIII) are efficiently prepared via kinetic resolution of the racemic alcohol (I) and used for the synthesis of chiral acids (VI) and (IX) by Ireland-Claisen rearrangement. -(MARHOLD, M.; WITTMANN, U.; GRIMME, S.; TAKAHASHI, T.; HAUFE*, G.; J. Fluorine